ArticleGenes2016
Systematic Analysis of the 4-Coumarate:Coenzyme A Ligase (4CL) Related Genes and Expression Profiling during Fruit Development in the Chinese Pear.
Article in Genes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 64 citations in OpenAlex.
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- Integrated omics analysis identified genes and their splice variants involved in fruit development and metabolites production in Capsicum species.Functional & integrative genomics · 2022Article
- Comparative Genomic Analysis ofInternational journal of molecular sciences · 2022Article
- Systematic Analysis and Expression Profiles of the 4-Coumarate: CoA Ligase (4CL) Gene Family in Pomegranate (International journal of molecular sciences · 2022Article
- Pear genetics: Recent advances, new prospects, and a roadmap for the future.Horticulture research · 2022Article
- Dissection of leucine-rich repeat receptor-like protein kinases: insight into resistance toPeerJ · 2022Article
- Flavonoids Accumulation in Fruit Peel and Expression Profiling of Related Genes in Purple (Plants (Basel, Switzerland) · 2021Article
- PbCSE1 promotes lignification during stone cell development in pear (Pyrus bretschneideri) fruit.Scientific reports · 2021Article
- Integrated transcriptomic and proteomic analysis reveals the complex molecular mechanisms underlying stone cell formation in Korla pear.Scientific reports · 2021Article
- Functional analysis of four Class III peroxidases from Chinese pear fruit: a critical role in lignin polymerization.Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- First Report of CRISPR/Cas9 Mediated DNA-Free Editing ofInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, 4-coumarate:coenzyme A ligases (4CLs), comprising some of the adenylate-forming enzymes, are key enzymes involved in regulating lignin metabolism and the biosynthesis of flavonoids and other secondary metabolites. Although several 4CL-related proteins were shown to play roles in secondary metabolism, no comprehensive study on 4CL-related genes in the pear and other Rosaceae species has been reported. In this study, we identified 4CL-related genes in the apple, peach, yangmei, and pear genomes using DNATOOLS software and inferred their evolutionary relationships using phylogenetic analysis, collinearity analysis, conserved motif analysis, and structure analysis. A total of 149 4CL-related genes in four Rosaceous species (pear, apple, peach, and yangmei) were identified, with 30 members in the pear. We explored the functions of several 4CL and acyl-coenzyme A synthetase (ACS) genes during the development of pear fruit by quantitative real-time PCR (qRT-PCR). We found that duplication events had occurred in the 30 4CL-related genes in the pear. These duplicated 4CL-related genes are distributed unevenly across all pear chromosomes except chromosomes 4, 8, 11, and 12. The results of this study provide a basis for further investigation of both the functions and evolutionary history of 4CL-related genes.
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