ArticleACS applied materials & interfaces2016
Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting.
Article in ACS applied materials & interfaces, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Stable, bioactive hydrogel coating on silicone surfaces for non-invasive decontamination via photochemical treatment.Bioactive materials · 2025Article
- Enhancing the Interfacial Adhesion of a Ductile Gold Electrode with PDMS Using an Interlocking Structure for Applications in Temperature Sensors.Nanomaterials (Basel, Switzerland) · 2025Article
- Preparation and properties of silver-carrying nano-titanium dioxide antimicrobial agents and silicone composite.Scientific reports · 2024Article
- Silicones for Maxillofacial Prostheses and Their Modifications in Service.Materials (Basel, Switzerland) · 2024Review
- Antimicrobial Functionalization of Silicone-graft-poly(Molecules (Basel, Switzerland) · 2024Article
- Photodynamic toluidine blue-gold nanoconjugates as a novel therapeutic forRSC advances · 2023Article
- Microbial growth and adhesion of Escherichia coli in elastomeric silicone foams with commonly used additives.Scientific reports · 2023Article
- Antibacterial-Based Hydrogel Coatings and Their Application in the Biomedical Field-A Review.Journal of functional biomaterials · 2023Review
- Development of a Flow-free Gradient Generator Using a Self-Adhesive Thiol-acrylate Microfluidic Resin/Hydrogel (TAMR/H) Hybrid System.ACS applied materials & interfaces · 2021Article
- Preparation and properties of room temperature vulcanized silicone rubber based on rosin-grafted polydimethylsiloxane.RSC advances · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Biomedical devices are indispensable in modern medicine yet offer surfaces that promote bacterial attachment and biofilm formation, resulting in acute and chronic healthcare-associated infections. We have developed a simple method to graft acrylates to silicone rubber, polydimethylsiloxane (PDMS), a commonly used device material that is often colonized by bacteria. We demonstrate a novel method whereby nontoxic bacteria attachment-resistant polymers can be readily grafted from and grafted to the surface using thiol-ene chemistry, substantially reducing bacterial colonization. With use of this approach, bacterial biofilm coverage can be reduced by 99% compared with standard PDMS in an in vitro assay. This grafting approach offers significant advantages over commonly used physisorbed coatings, especially in areas of high shear or mechanical stress. Furthermore, the approach is versatile such that the grafted material properties can be tailored for the desired final application.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.