Evidence map›Paper›PMID 27775116›Full record

ArticleChemical communications (Cambridge, England)2016

Protocol for the purification of protected carbohydrates: toward coupling automated synthesis to alternate-pump recycling high-performance liquid chromatography.

Gabe Nagy, Tianyuan Peng, Daniel E K Kabotso, Milos V Novotny, Nicola L B Pohl

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. HPLC-Based Automated Synthesis of Glycans in Solution.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gabe NagyDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA. npohl@indiana.edu.
Tianyuan PengDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA. npohl@indiana.edu.
Daniel E K KabotsoDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA. npohl@indiana.edu.
Milos V NovotnyDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA. npohl@indiana.edu.
Nicola L B PohlDepartment of Chemistry, Indiana University, Bloomington, IN 47405, USA. npohl@indiana.edu.
Bloomington Health Foundation · USIndiana University · USIndiana University Bloomington · US

Funding

Sugar Building Blocks and Automated Synthesis of Biomedically-Relevant GlycansU01GM116248 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI POHL, NICOLA L. B. · 2015 to 2019
$2.7M
NIGMS NIH HHS U01 GM116248
6 · The paper itself

Abstract

Given recent advances in automated oligosaccharide synthesis, analytical techniques that can be coupled to a synthetic framework are needed to not just identify but also purify to homogeneity protected carbohydrate compounds at levels of ≥99.5% purity. Herein, an alternate-pump recycling high-performance liquid chromatography (R-HPLC) method has been developed to allow purification of protected carbohydrates at levels of ≥99.5% purity.

Identifiers

PMID27775116
PMCPMC5123635
OpenAlexW2533453780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.