Evidence map›Paper›PMID 27775017›Full record

ArticleScientific reports2016

Multifunctional SPIO/DOX-loaded A54 Homing Peptide Functionalized Dextran-g-PLGA Micelles for Tumor Therapy and MR Imaging.

Jun-Qing Situ, Xiao-Juan Wang, Xiu-Liang Zhu, Xiao-Ling Xu, Xu-Qi Kang, Jing-Bo Hu, Chen-Ying Lu, Xiao-Ying Ying, Ri-Sheng Yu, Jian You and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jun-Qing SituCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Xiao-Juan WangCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Xiu-Liang ZhuDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Xiao-Ling XuCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Xu-Qi KangCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Jing-Bo HuCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Chen-Ying LuDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Xiao-Ying YingCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Ri-Sheng YuDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Jian YouCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Yong-Zhong DuCollege of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific delivery of chemotherapy drugs and magnetic resonance imaging (MRI) contrast agent into tumor cells is one of the issues to highly efficient tumor targeting therapy and magnetic resonance imaging. Here, A54 peptide-functionalized poly(lactic-co-glycolic acid)-grafted dextran (A54-Dex-PLGA) was synthesized. The synthesized A54-Dex-PLGA could self-assemble to form micelles with a low critical micelle concentration of 22.51 μg. mL

Indexed as

AnimalsAntineoplastic AgentsCarcinoma, HepatocellularCell Line, TumorContrast MediaDisease Models, AnimalDoxorubicinDrug CarriersFerric CompoundsHistocytochemistryHumansLactic AcidLiver NeoplasmsMagnetic Resonance ImagingMice, NudeMicroscopyAntineoplastic AgentsContrast MediaDoxorubicinDrug CarriersFerric Compoundsferric oxideLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymer

Identifiers

PMID27775017
PMCPMC5075939

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.