ArticleJournal of the International AIDS Society2016
Incidence of syphilis seroconversion among HIV-infected persons in Asia: results from the TREAT Asia HIV Observational Database.
Article in Journal of the International AIDS Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta-analysis.Journal of the International AIDS Society · 2025Pooled it
- Clinical manifestations and serological rebound in HIV and syphilis co-infection: a case report and literature review.AIDS research and therapy · 2026Review
- High Incidence of syphilis seroconversion among people living with HIV in Hainan, south China.Scientific reports · 2024Article
- Temporal Trends in Syphilis Incidence among Men with HIV in Busan, Korea, 2005-2022: A Retrospective Cohort Study.Viruses · 2024Article
- Prevalence, risk factors and treatment outcomes of syphilis among people living with human immunodeficiency virus at primary care clinics in Malaysia: A retrospective study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024Article
- Article
- Effects of syphilis infection among HIV-1-positive individuals on suppressive antiretroviral therapy.AIDS research and therapy · 2022Article
- Control of sexually transmitted infections and global elimination targets, South-East Asia Region.Bulletin of the World Health Organization · 2021Review
- Incidence of syphilis among HIV-infected men in Singapore, 2006-2017: temporal trends and associated risk factors.Sexually transmitted infections · 2020Article
- A field evaluation of a rapid dual immunoassay for human immunodeficiency virus and syphilis antibodies, Hanoi, Vietnam.International journal of STD & AIDS · 2019Article
- Changes of sexual risk behaviors and sexual connections among HIV-positive men who have sex with men along their HIV care continuum.PloS one · 2018Article
- Syphilis Infection Differentially Regulates the Phenotype and Function of γδ T Cells in HIV-1-Infected Patients Depends on the HIV-1 Disease Stage.Frontiers in immunology · 2017Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
introductionOutbreaks of syphilis have been described among HIV-infected men who have sex with men (MSM) in Western communities, whereas reports in Asian countries are limited. We aimed to characterize the incidence and temporal trends of syphilis among HIV-infected MSM compared with HIV-infected non-MSM in Asian countries.
methodsPatients enrolled in the TREAT Asia HIV Observational Database cohort and with a negative non-treponemal test since enrolment were analyzed. Incidence of syphilis seroconversion, defined as a positive non-treponemal test after previously testing negative, was evaluated among patients at sites performing non-treponemal tests at least annually. Factors associated with syphilis seroconversion were investigated at sites doing non-treponemal testing in all new patients and subsequently testing routinely or when patients were suspected of having syphilis.
resultsWe included 1010 patients from five sites that performed non-treponemal tests in all new patients; those included had negative non-treponemal test results during enrolment and subsequent follow-ups. Among them, 657 patients were from three sites conducting regular non-treponemal testing. The incidence of syphilis seroconversion was 5.38/100 person-years (PY). Incidence was higher in MSM than non-MSM (7.64/100 PY vs. 2.44/100 PY,
conclusionsWe observed a higher incidence of syphilis seroconversion among HIV-infected MSM and a trend to increasing annual incidence. Regular screening for syphilis and targeted interventions to limit transmission are needed in this population.
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