Evidence map›Paper›PMID 27774819›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2017

Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations.

Marcello Locatelli, Gokhan Zengin, Ahmet Uysal, Simone Carradori, Elisa De Luca, Giuseppe Bellagamba, Abdurrahman Aktumsek, Irina Lazarova

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. A Four-Decade Bibliometric Analysis on the Genera,Plants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. 3 Biotech · 2023
    Article
  5. Phytochemical characterization ofFrontiers in chemistry · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Benzo[Journal of enzyme inhibition and medicinal chemistry · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Phenolic Profile and Bioactivities ofFrontiers in pharmacology · 2019
    Article
  15. Article
  16. Article
  17. Molecules (Basel, Switzerland) · 2018
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcello Locatellia Department of Pharmacy , University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Gokhan Zenginc Science Faculty, Department of Biology , Selcuk University , Konya , Turkey.
Ahmet Uysald Deparment of Medicinal Laboratory, Vocational School of Health Services , Selcuk University , Turkey.
Simone Carradoria Department of Pharmacy , University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Elisa De Lucaa Department of Pharmacy , University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Giuseppe Bellagambaa Department of Pharmacy , University "G. d'Annunzio" of Chieti-Pescara , Chieti , Italy.
Abdurrahman Aktumsekc Science Faculty, Department of Biology , Selcuk University , Konya , Turkey.
Irina Lazarovae Department of Chemistry, Faculty of Pharmacy , Medical University of Sofia , Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product. Free anthraquinones and phenolics were determined using validated HPLC-PDA methods. Antioxidant properties were determined by different procedures including free radical scavenging, reducing power, phosphomolybdenum and metal chelating assays. Ames assay was performed to evaluate mutagenic/antimutagenic properties. Enzyme inhibitory activities were tested against cholinesterase, tyrosinase, α-amylase and α-glucosidase. From the herein reported results, Asphodeline could be valuable for the production of bioactive products or food supplements for cosmetic and pharmaceutical industries.

Indexed as

alpha-AmylasesAsparagalesChromatography, High Pressure Liquidalpha-AmylasesanthraquinonesAsphodelinebiological activity and bioactive compoundsmulticomponent patternphenolics

Identifiers

PMID27774819
PMCPMC6010134

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.