Evidence map›Paper›PMID 27774695›Full record

ArticleHuman brain mapping2017

Similarities and differences in the default mode network across rest, retrieval, and future imagining.

B Bellana, Z-X Liu, N B Diamond, C L Grady, M Moscovitch

Open access · greenAbstract read
In one paragraph

Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  14. Estimated Regional White Matter Hyperintensity Burden, Resting State Functional Connectivity, and Cognitive Functions in Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
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  19. Observational
  20. The contributions of the endocannabinoid system and stress on the neural processing of reward stimuli.Progress in neuro-psychopharmacology & biological psychiatry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

B BellanaDepartment of Psychology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-0266-8800
Z-X LiuRotman Research Institute - Baycrest, Toronto, Ontario, Canada.
N B DiamondDepartment of Psychology, University of Toronto, Toronto, Ontario, Canada.
C L GradyDepartment of Psychology, University of Toronto, Toronto, Ontario, Canada.
M MoscovitchDepartment of Psychology, University of Toronto, Toronto, Ontario, Canada.
University of Toronto · CA

Funding

CIHR MOP14036
6 · The paper itself

Abstract

The default mode network (DMN) has been identified reliably during rest, as well as during the performance of tasks such as episodic retrieval and future imagining. It remains unclear why this network is engaged across these seemingly distinct conditions, though many hypotheses have been proposed to account for these effects. Prior to generating hypotheses explaining common DMN involvement, the degree of commonality in the DMN across these conditions, within individuals, must be statistically determined to test whether or not the DMN is truly a unitary network, equally engaged across rest, retrieval and future imagining. To provide such a test, we used comparable paradigms (self-directed, uninterrupted thought of equal duration) across the three conditions (rest, retrieval, and future imagining) in a within-participant design. We found lower than expected pattern similarity in DMN functional connectivity across the three conditions. Similarity in connectivity accounted for only 40-50% of the total variance. Partial Least Squares (PLS) analyses revealed the medial temporal regions of the DMN were preferentially coupled with one another during episodic retrieval and future imagining, whereas the non-medial temporal regions of the DMN (e.g., medial prefrontal cortex, lateral temporal cortex, and temporal pole) were preferentially coupled during rest. These results suggest that DMN connectivity may be more flexible than previously considered. Our findings are in line with emerging evidence that the DMN is not a static network engaged commonly across distinct cognitive processes, but is instead a dynamic system, topographically changing in relation to ongoing cognitive demands. Hum Brain Mapp 38:1155-1171, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

Image Processing, Computer-AssistedModels, NeurologicalAdolescentAnalysis of VarianceBrainBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysRestThinkingYoung Adultdefault mode networkepisodic memoryfunctional connectivityfuture imaginingresting state

Identifiers

PMID27774695
PMCPMC6866996
OpenAlexW2541281100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.