ArticleCurrent opinion in behavioral sciences2017
Is biological aging accelerated in drug addiction?
Article in Current opinion in behavioral sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Evidence-based consensus guidelines for the pharmacological management of substance dependence: Recommendations from the British Association for Psychopharmacology.Journal of psychopharmacology (Oxford, England) · 2026Guideline
- Effects of substance use disorder on oxidative and antioxidative stress markers: A systematic review and meta-analysis.Addiction biology · 2023Pooled it
- Intervention effects on self-control decrease speed of biological aging mediated by changes in substance use: A longitudinal study of African American youth.Family process · 2022Trial
- Young Adult Substance Use as a Predictor of Poor Self-Rated Memory Decades Later in Midlife.Journal of aging and health · 2026Article
- Older Age Is Associated With Long-Term Retention in Buprenorphine Treatment for Opioid Use Disorder.Journal of the American Geriatrics Society · 2026Article
- The Impaired Response Inhibition and Salience Attribution Model of Drug Addiction: Recent Neuroimaging Evidence and Future Directions.Annual review of psychology · 2026Review
- The predictivity of hematological parameters and related inflammatory biomarkers of male subjects with chronic polysubstance use disorder.Brain, behavior, & immunity - health · 2025Article
- Supporting older-adult behavioral health: building the first state Center of Excellence for Behavioral Health and Aging.Health affairs scholar · 2025Review
- Leveraging Genomic Data to Examine the Causal Impact of Alcohol, Tobacco, Cannabis, and Opioid Use on Biological and Cognitive Ageing.Addiction biology · 2025Article
- Incidence, Patient-Directed Discharge, Readmission, and Mortality Among People Hospitalized With Injecting-Related Infection: A Population-Based Linkage Study.Open forum infectious diseases · 2025Article
- Changing age profile and incidence of injecting drug use initiation among people in Australia who inject drugs: evidence from two national repeated cross-sectional studies.The Lancet regional health. Western Pacific · 2025Article
- Synthetic Cathinones Induce Developmental Arrest, Reduce Reproductive Capacity, and Shorten Lifespan in theJournal of xenobiotics · 2025Article
- Tailoring Treatment for Substance Use Disorders in Older Adults: A Mixed-methods Study.Innovation in aging · 2025Article
- Examining the causal genetic effects of substance use on aging.medRxiv : the preprint server for health sciences · 2024Article
- Frailty and Cardiovascular Health.Journal of the American Heart Association · 2024Review
- The Impact of Childhood Mental Health and Substance Use on Methylation Aging Into Adulthood.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Article
- Molecular signatures of premature aging in Major Depression and Substance Use Disorders.Scientific data · 2024Article
- Older adult drug overdose: an application of latent class analysis to identify prevention opportunities.Harm reduction journal · 2024Article
- Accidental substance-related acute toxicity deaths in older adults in 2016 and 2017: a national chart review study.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2024Article
- Differences in heroin overdose deaths in Australia by age, 2020-2022: Disease and estimated survival times.Drug and alcohol dependence reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Drug-addiction may trigger early onset of age-related disease, due to drug-induced multi-system toxicity and perilous lifestyle, which remains mostly undetected and untreated. We present the literature on pathophysiological processes that may hasten aging and its relevance to addiction, including: oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume and function, and early onset of cardiac, cerebrovascular, kidney, and liver disease. Timely detection of accelerated aging in addiction is crucial for the prevention of premature morbidity and mortality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.