Evidence map›Paper›PMID 27774468›Full record

ReviewHypoxia (Auckland, N.Z.)2014

The role of PHD2 mutations in the pathogenesis of erythrocytosis.

Betty Gardie, Melanie J Percy, David Hoogewijs, Rasheduzzaman Chowdhury, Celeste Bento, Patrick R Arsenault, Stéphane Richard, Helena Almeida, Joanne Ewing, Frédéric Lambert and 3 more

Open access · diamondAbstract readReview
In one paragraph

Review in Hypoxia (Auckland, N.Z.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Time-resolved NMR detection of prolyl-hydroxylation in intrinsically disordered region of HIF-1α.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Novel GermlineMedicina (Kaunas, Lithuania) · 2022
    Article
  15. Erythrocytosis associated withHaematologica · 2022
    Article
  16. Article
  17. Erythrocytosis: genes and pathways involved in disease development.Blood transfusion = Trasfusione del sangue · 2021
    Review
  18. Article
  19. Article
  20. Hypoxia Pathway Proteins are Master Regulators of Erythropoiesis.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 5 countries.

Betty GardieLaboratoire de Génétique Oncologique de l'Ecole Pratique des Hautes Etudes, Villejuif; Unité Mixte de Recherche, Institut national de la santé et de la recherche médicale U892, Centre national de la recherche scientifique 6299, Centre de Recherche en Cancérologie Nantes/Angers, Université de Nantes, Nantes, France.
Melanie J PercyDepartment of Haematology, Belfast City Hospital, Belfast, UK.
David HoogewijsInstitute of Physiology and Zürich Center for Integrative Human Physiology, University of Zürich, Zürich, Switzerland.
Rasheduzzaman ChowdhuryDepartment of Chemistry and Oxford Centre for Integrative Systems Biology, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Celeste BentoDepartment of Hematology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Patrick R ArsenaultDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Stéphane RichardLaboratoire de Génétique Oncologique de l'Ecole Pratique des Hautes Etudes, Villejuif; Institut national de la santé et de la recherche médicale U753, Institut de cancérologie Gustave Roussy (IGR), Villejuif, France; Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France.
Helena AlmeidaDepartment of Hematology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Joanne EwingHeart of England NHS Trust, Birmingham, UK.
Frédéric LambertCenter for Human Genetics, Pathology Institute, UniLab-Lg, Molecular Haemato-Oncology Unit, CHU of Liege, Liege, Belgium.
Mary Frances McMullinDepartment of Haematology, Queen's University, Belfast, UK.
Christopher J SchofieldDepartment of Chemistry and Oxford Centre for Integrative Systems Biology, Chemistry Research Laboratory, University of Oxford, Oxford, UK.
Frank S LeeDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Hospitais da Universidade de Coimbra · PTUniversity of Oxford · GBUniversity of Pennsylvania · USHeart of England NHS Foundation Trust · GBInstitut Gustave Roussy · FRNantes Université · FRQueen's University Belfast · GBUniversity of Ulster · GBUniversity of Zurich · CH

Funding

HEMATOPOIESIS TRAINING GRANTT32DK007780 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI TONG, WEI · 1999 to 2023
$6.7M
6 · The paper itself

Abstract

The transcription of the erythropoietin (

Indexed as

EGLN1erythrocytosiserythropoietinHIFhypoxiaPHD2

Identifiers

PMID27774468
PMCPMC5045058
OpenAlexW2031972302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.