Evidence map›Paper›PMID 27774450›Full record

ArticleFrontiers in molecular biosciences2016

Effects of a Mutation in the

Anne S Bie, Paula Fernandez-Guerra, Rune I D Birkler, Shahar Nisemblat, Dita Pelnena, Xinping Lu, Joshua L Deignan, Hane Lee, Naghmeh Dorrani, Thomas J Corydon and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. HSP60 and HSP10 depletion provoke distinct biological responses.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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  4. Heat shock protein 10 as a chaperone modulating α-synuclein amyloid fibril formation.Protein science : a publication of the Protein Society · 2026
    Article
  5. Biomolecular NMR assignments · 2025
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  19. Article
  20. A recurrent de novoCold Spring Harbor molecular case studies · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Anne S BieResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Paula Fernandez-GuerraResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Rune I D BirklerResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Shahar NisemblatDepartment of Biochemistry & Molecular Biology, Tel Aviv University Tel Aviv, Israel.
Dita PelnenaResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Xinping LuDepartment of Biochemistry & Molecular Biology, Tel Aviv University Tel Aviv, Israel.
Joshua L DeignanDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles Los Angeles, CA, USA.
Hane LeeDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles Los Angeles, CA, USA.
Naghmeh DorraniDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los AngelesLos Angeles, CA, USA; Department of Pediatrics, David Geffen School of Medicine at University of California, Los AngelesLos Angeles, CA, USA.
Thomas J CorydonDepartment of Biomedicine, Aarhus University Aarhus, Denmark.
Johan PalmfeldtResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Liga BivinaDivision of Genomic Medicine, Department of Pediatrics, UC Davis Health System Sacramento, CA, USA.
Abdussalam AzemDepartment of Biochemistry & Molecular Biology, Tel Aviv University Tel Aviv, Israel.
Kristin HermanDivision of Genomic Medicine, Department of Pediatrics, UC Davis Health System Sacramento, CA, USA.
Peter BrossResearch Unit for Molecular Medicine, Aarhus University and Aarhus University Hospital Aarhus, Denmark.
Aarhus University Hospital · DKTel Aviv University · ILUniversity of California, Los Angeles · USUC Davis Health System · USAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We here report molecular investigations of a missense mutation in the

Indexed as

De novo mutationsmitochondrial proteinsmolecular chaperonesneurological disordersoxidative stressprotein folding

Identifiers

PMID27774450
PMCPMC5053987
OpenAlexW2529485150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.