Evidence map›Paper›PMID 27774374›Full record

ArticleBioNanoScience2016

Magnetic Nanodrug Delivery Through the Mucus Layer of Air-Liquid Interface Cultured Primary Normal Human Tracheobronchial Epithelial Cells.

E C Economou, S Marinelli, M C Smith, A A Routt, V V Kravets, H W Chu, K Spendier, Z J Celinski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioNanoScience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. A comparison of three mucus-secreting airway cell lines (Calu-3, SPOC1 and UNCN3T) for use as biopharmaceutical models of the nose and lung.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

E C EconomouCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA ; Department of Physics and Energy Science, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA.
S MarinelliCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA.
M C SmithCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA.
A A RouttCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA.
V V KravetsCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA ; Department of Physics and Energy Science, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA.
H W ChuDepartment of Medicine, National Jewish Health, Denver, CO 80206, USA.
K SpendierCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA ; Department of Physics and Energy Science, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA.
Z J CelinskiCenter of the BioFrontiers Institute, University of Colorado at Colorado Springs, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA ; Department of Physics and Energy Science, University of Colorado at Colorado Springs, Colorado Springs, CO 80918, USA.

Funding

IRAK-M in lung defense against rhinovirus infectionR01AI106287 · NIAID · NATIONAL JEWISH HEALTH · PI CHU, HONG W, LI, LIWU · 2014 to 2018
$2.0M
SPLUNC1 in Severe AsthmaR01HL125128 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHU, HONG W, DI, YUANPU PETER · 2015 to 2018
$1.9M
Novel function of MUC18: amplification of inflammation in allergic lungsR01HL122321 · NHLBI · NATIONAL JEWISH HEALTH · PI CHU, HONG W · 2015 to 2018
$1.6M
NHLBI NIH HHS R01 HL122321NHLBI NIH HHS R01 HL125128NIAID NIH HHS R01 AI106287
6 · The paper itself

Abstract

Superparamagnetic iron oxide (Fe

Indexed as

Barium hexaferriteDexamethasoneDrug deliveryHigh anisotropy magnetic nanoparticlesMucus overproductionNanomedicineNanotherapeutics

Identifiers

PMID27774374
PMCPMC5070545

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.