Evidence map›Paper›PMID 27774259›Full record

ArticleESC heart failure2015

Prognostic implication of right ventricular involvement in peripartum cardiomyopathy: a cardiovascular magnetic resonance study.

Arash Haghikia, Philipp Röntgen, Jens Vogel-Claussen, Johannes Schwab, Ralf Westenfeld, Philipp Ehlermann, Dominik Berliner, Edith Podewski, Denise Hilfiker-Kleiner, Johann Bauersachs

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Trial
  5. Trial
  6. Review
  7. Cardiovascular complications of pregnancy.The Journal of clinical investigation · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Pregnancy-Related Cardiovascular Diseases: A Radiological Overview.Journal of cardiovascular development and disease · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. What Do We Know about Peripartum Cardiomyopathy? Yesterday, Today, Tomorrow.International journal of molecular sciences · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Arash HaghikiaDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Philipp RöntgenDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Jens Vogel-ClaussenInstitute of Diagnostic and Interventional Radiology Hannover Medical School Hannover Germany.
Johannes SchwabDepartment of Cardiology Paracelsus Medical University, General Hospital Nuernberg Nuernberg Germany.
Ralf WestenfeldDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty University Duesseldorf Germany.
Philipp EhlermannDepartment of Cardiology, Pulmonology, and Vascular Medicine University of Heidelberg Heidelberg Germany.
Dominik BerlinerDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Edith PodewskiDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Denise Hilfiker-KleinerDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Johann BauersachsDepartment of Cardiology and Angiology Hannover Medical School Hannover Germany.
Medizinische Hochschule Hannover · DEDüsseldorf University Hospital · DEParacelsus Medizinische Privatuniversität · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPeripartum cardiomyopathy (PPCM) is a major cause of acute heart failure in the peripartum period and considered potentially life threatening. While many aspects of its clinical profiles have been frequently reported, functional analysis, in particular of the right ventricle, and tissue characterization by cardiovascular magnetic resonance (CMR) imaging have been only sporadically described. The aim of the present study was to analyse pathological alterations and their prognostic relevance found in CMR imaging of patients newly diagnosed with PPCM. METHODS AND

resultsIn this multicenter study 34 patients with confirmed PPCM underwent CMR imaging at the time of diagnosis and at 5 ± 1 months follow-up. Cine imaging of PPCM patients showed moderate to severe reduction of systolic left ventricular (LV) function (mean LVEF: 29.7 ± 12.8%). In 35% of the patients right ventricular (RV) systolic function was also reduced with a mean RVEF of 42.9 ± 13.9%. Dilatation of the LV was observed in 91% (mean LV-EDV/BSA 128.5 ± 32.1 mL/m

conclusionsBesides LV systolic dysfunction, RV dysfunction and dilatation are observed in about one third of PPCM patients at the time of diagnosis. RV dysfunction is associated with unfavourable outcome. A distinct pattern of LV wall motion abnormalities and myocardial scar is evident in most PPCM patients. The present study may help to establish a set of CMR criteria suitable for diagnosis in patients with suspected PPCM and may add further knowledge to the pathology of the disease.

Indexed as

Multiparametric cardiovascular magnetic resonance imagingPeripartum cardiomyopathyRight ventricular involvement

Identifiers

PMID27774259
PMCPMC5054874
OpenAlexW1834562274

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.