ArticleESC heart failure2015
Single baseline serum creatinine measurements predict mortality in critically ill patients hospitalized for acute heart failure.
Article in ESC heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Prognostic implications of a four-group classification based on estimated plasma volume status and creatinine in acute heart failure.Heart and vessels · 2026Article
- Endothelial Activation and Stress Index (EASIX) Predicts In-Hospital Mortality in Acute Decompensated Heart Failure with Reduced Ejection Fraction.Diagnostics (Basel, Switzerland) · 2026Article
- Twist2 knockdown alleviates renal ischemia-reperfusion injury by maintaining mitochondrial function and enhancing mitophagy through Bnip3.Human cell · 2025Article
- Association between the blood urea nitrogen to creatinine ratio and in‑hospital mortality among patients with acute myocardial infarction: A retrospective cohort study.Experimental and therapeutic medicine · 2023Article
- Development and Validation of a Risk Score in Chinese Patients With Chronic Heart Failure.Frontiers in cardiovascular medicine · 2022Article
- Predictive values of blood urea nitrogen/creatinine ratio and other routine blood parameters on disease severity and survival of COVID-19 patients.Journal of medical virology · 2021Article
- Observational
- Iron therapy in heart failure patients without anaemia: possible implications for chronic kidney disease patients.Clinical kidney journal · 2017Review
- Lack of evidence of lower 30-day all-cause readmission in Medicare beneficiaries with heart failure and reduced ejection fraction discharged on spironolactone.International journal of cardiology · 2017Article
- Single baseline serum creatinine measurements predict mortality in critically ill patients hospitalized for acute heart failure.ESC heart failure · 2015Article
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute heart failure (AHF) is a leading cause of death in critically ill patients and is often accompanied by significant renal dysfunction. Few data exist on the predictive value of measures of renal dysfunction in large cohorts of patients hospitalized for AHF.
methodsSix hundred and eighteen patients hospitalized for AHF (300 male, aged 73.3 ± 10.3 years, 73% New York Heart Association Class 4, mean hospital length of stay 12.9 ± 7.7 days, 97% non-ischaemic AHF) were included in a retrospective single-centre data analysis. Echocardiographic data, serum creatinine/urea levels, estimated glomerular filtration rate (eGFR), and clinical/laboratory markers were recorded. Mean follow-up time was 2.9 ± 2.1 years. All-cause mortality was recorded, and univariate/multivariate analyses were performed.
resultsNormal renal function defined as eGFR > 90 mL/min/1.73 m
conclusionsIn a large cohort of patients with mostly non-ischaemic AHF, enhanced serum creatinine levels and reduced eGFR independently predict death. It appears that patients with eGFR < 30 mL/min/1.73 m
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