Evidence map›Paper›PMID 27774144›Full record

ArticleRSC advances2016

Self-Strengthening Hybrid Dental Adhesive via Visible-light Irradiation Triple Polymerization.

Linyong Song, Qiang Ye, Xueping Ge, Anil Misra, Candan Tamerler, Paulette Spencer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Photoacid Generators for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Threats to adhesive/dentin interfacial integrity and next generation bio-enabled multifunctional adhesives.Journal of biomedical materials research. Part B, Applied biomaterials · 2019
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Linyong SongUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.
Qiang YeUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.
Xueping GeUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.
Anil MisraUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.; University of Kansas, Department of Civil Engineering, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.
Candan TamerlerUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.; University of Kansas, Department of Mechanical Engineering, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.
Paulette SpencerUniversity of Kansas, Bioengineering Research Center, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.; University of Kansas, Department of Mechanical Engineering, 1530 W. 15th Street, Lawrence, KS 66045-7609, USA.

Funding

Peptide-Polymer Engineering Dentin/Adhesive Interfacial Bond IntegrityR01DE025476 · NIDCR · UNIVERSITY OF KANSAS LAWRENCE · PI SPENCER, PAULETTE, TAMERLER-BEHAR, CANDAN · 2015 to 2024
$3.2M
Proton Sponge Adhesives, Interfacial Milieu: Molecular Structure-MechanicsR01DE022054 · NIDCR · UNIVERSITY OF KANSAS LAWRENCE · PI LAURENCE, JENNIFER S., SPENCER, PAULETTE · 2011 to 2015
$2.0M
NIDCR NIH HHS R01 DE022054NIDCR NIH HHS R01 DE025476
6 · The paper itself

Abstract

A self-strengthening methacrylate-based dental adhesive system was developed by introducing an epoxy cyclohexyl trimethoxysilane (TS) which contains both epoxy and methoxysilyl functional groups. The experimental formulation, HEMA/BisGMA/TS (22.5/27.5/50, wt%), was polymerized by visible-light. Real-time Fourier transform infrared spectroscopy (FTIR) was used to investigate in situ the free radical polymerization of methacrylate, ring-opening cationic polymerization of epoxy, and photoacid-induced sol-gel reactions. Among the three simultaneous reactions, the reaction rate of the free radical polymerization was the highest and the hydrolysis/condensation rate was the lowest. With 40s-irradiation, the degrees of conversion of the double bond and epoxy groups at 600 s were 73.2±1.2%, 87.9±2.4%, respectively. Hydrolysis of the methoxysilyl group was initially <5%, and increased gradually to about 50% after 48 h dark storage. Photoacids generated through the visible-light-induced reaction were effective in catalyzing both epoxy ring-opening polymerization and methoxysilyl sol-gel reaction. The mechanical properties of copolymers made with TS concentrations from 5 to 35 wt% were obtained using dynamic mechanical analysis (DMA). In wet conditions, the storage moduli at 70 °C and glass transition temperature were significantly higher than that of the control (p<0.05); these properties increased with TS concentration and storage time. The post reaction of hydrolysis/condensation of alkoxysilane could provide persistent strengthening whether in a neutral or acidic environment and these characteristics could lead to enhanced mechanical properties in the oral environment. The cumulative amount of leached species decreased significantly in the TS-containing copolymers. These results provide valuable information for the development of dental adhesives with reduced leaching of methacrylate monomers and enhanced mechanical properties under the wet, oral environment.

Identifiers

PMID27774144
PMCPMC5070808

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.