Evidence map›Paper›PMID 27774126›Full record

ArticleACS medicinal chemistry letters2016

Exploring

Nilgun Isik Reed, You-Zhi Tang, Joel McIntosh, Yibing Wu, Kathleen S Molnar, Annafelicia Civitavecchia, Dean Sheppard, William F DeGrado, Hyunil Jo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Therapeutic molecular targets of SSc-ILD.Journal of scleroderma and related disorders · 2020
    Article
  5. Shared and distinct mechanisms of fibrosis.Nature reviews. Rheumatology · 2019
    Review
  6. Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease.Matrix biology : journal of the International Society for Matrix Biology · 2018
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nilgun Isik ReedDepartment of Medicine, University of California-San Francisco , San Francisco, California 94153, United States.
You-Zhi TangDepartment of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, California 94158, United States; College of Veterinary Medicine, South China Agricultural University, Guangdong 510642, China.
Joel McIntoshDepartment of Pharmaceutical Chemistry, University of California-San Francisco , San Francisco, California 94158, United States.
Yibing WuDepartment of Pharmaceutical Chemistry, University of California-San Francisco , San Francisco, California 94158, United States.
Kathleen S MolnarDepartment of Pharmaceutical Chemistry, University of California-San Francisco , San Francisco, California 94158, United States.
Annafelicia CivitavecchiaDepartment of Pharmaceutical Chemistry, University of California-San Francisco , San Francisco, California 94158, United States.
Dean SheppardDepartment of Medicine, University of California-San Francisco , San Francisco, California 94153, United States.
William F DeGradoDepartment of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, California 94158, United States; Cardiovascular Research Institute, University of California-San Francisco, San Francisco, California 94158, United States.
Hyunil JoDepartment of Pharmaceutical Chemistry, University of California-San Francisco , San Francisco, California 94158, United States.
University of California, San Francisco · USUniversity of San Francisco · US

Funding

Venoms, Biological Resources, Molecular BiologyP01GM048677 · NIGMS · UNIVERSITY OF UTAH · PI BANDYOPADHYAY, PRADIP K · 1993 to 2018
$32.2M
Proposal for Central California 900 MHZ NMR SpectrometerP41GM068933 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI WEMMER, DAVID E · 2003 to 2007
$5.9M
NIGMS NIH HHS P01 GM048677NIGMS NIH HHS P41 GM068933
6 · The paper itself

Abstract

One small molecule inhibitor of αvβ1 integrin,

Indexed as

Fibrosisintegrin antagonistphenylsulfonylprolineTGFβαvβ1 integrin

Identifiers

PMID27774126
PMCPMC5066160
OpenAlexW2512212266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.