Evidence map›Paper›PMID 27774124›Full record

ArticleACS medicinal chemistry letters2016

Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds.

Jiradanai Sarasamkan, Matthias Scheunemann, Nattayaporn Apaijai, Siripong Palee, Warisara Parichatikanond, Kuntarat Arunrungvichian, Steffen Fischer, Siriporn Chattipakorn, Winnie Deuther-Conrad, Gerrit Schüürmann and 2 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Selective αInternational journal of molecular sciences · 2023
    Article
  3. International journal of molecular sciences · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jiradanai SarasamkanCenter of Excellence for Innovation in Drug Design and Discovery, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Permoserstraße15, 04318 Leipzig, Germany; National Cyclotron and PET Centre, Chulabhorn Hospital, 54 Kamphaengphet 6 Road, Bangkok 10210, Thailand.
Matthias ScheunemannDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf , Permoserstraße15, 04318 Leipzig, Germany.
Nattayaporn ApaijaiNeurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University , Chiang Mai 50200, Thailand.
Siripong PaleeNeurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University , Chiang Mai 50200, Thailand.
Warisara ParichatikanondDepartment of Pharmacology, Faculty of Pharmacy, Mahidol University , 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.
Kuntarat ArunrungvichianCenter of Excellence for Innovation in Drug Design and Discovery, Faculty of Pharmacy, Mahidol University , 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.
Steffen FischerDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf , Permoserstraße15, 04318 Leipzig, Germany.
Siriporn ChattipakornNeurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University , Chiang Mai 50200, Thailand.
Winnie Deuther-ConradDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf , Permoserstraße15, 04318 Leipzig, Germany.
Gerrit SchüürmannDepartment of Ecological Chemistry, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße15, 04318 Leipzig, Germany; Institute for Organic Chemistry, Technical University Bergakademie Freiberg, Leipziger Straße29, 09596 Freiberg, Germany.
Peter BrustDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf , Permoserstraße15, 04318 Leipzig, Germany.
Opa VajraguptaCenter of Excellence for Innovation in Drug Design and Discovery, Faculty of Pharmacy, Mahidol University , 447 Sri-Ayutthaya Road, Bangkok 10400, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel quinuclidine

Indexed as

click chemistryNicotinic acetylcholine receptorpositron emission tomographyquinuclidine anti-1,2,3-triazole

Identifiers

PMID27774124
PMCPMC5066149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.