Evidence map›Paper›PMID 27774093›Full record

ArticleFrontiers in immunology2016

Supplementation with

Adriaan A van Beek, Bruno Sovran, Floor Hugenholtz, Ben Meijer, Joanne A Hoogerland, Violeta Mihailova, Corine van der Ploeg, Clara Belzer, Mark V Boekschoten, Jan H J Hoeijmakers and 7 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. The gut microbiome as a modulator of arterial function and age-related arterial dysfunction.American journal of physiology. Heart and circulatory physiology · 2024
    Review
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  8. Article
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  17. Malnutrition, poor post-natal growth, intestinal dysbiosis and the developing lung.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Adriaan A van BeekCell Biology and Immunology Group, Wageningen University, Wageningen, Netherlands; Top Institute Food and Nutrition, Wageningen, Netherlands; Gut Health and Food Safety, Institute of Food Research, Norwich, UK.
Bruno SovranTop Institute Food and Nutrition, Wageningen, Netherlands; Host Microbe Interactomics, Wageningen University, Wageningen, Netherlands.
Floor HugenholtzTop Institute Food and Nutrition, Wageningen, Netherlands; Laboratory of Microbiology, Wageningen University, Wageningen, Netherlands.
Ben MeijerCell Biology and Immunology Group, Wageningen University , Wageningen , Netherlands.
Joanne A HoogerlandCell Biology and Immunology Group, Wageningen University , Wageningen , Netherlands.
Violeta MihailovaCell Biology and Immunology Group, Wageningen University , Wageningen , Netherlands.
Corine van der PloegCell Biology and Immunology Group, Wageningen University , Wageningen , Netherlands.
Clara BelzerTop Institute Food and Nutrition, Wageningen, Netherlands; Laboratory of Microbiology, Wageningen University, Wageningen, Netherlands.
Mark V BoekschotenTop Institute Food and Nutrition, Wageningen, Netherlands; Human Nutrition, Wageningen University, Wageningen, Netherlands.
Jan H J HoeijmakersDepartment of Molecular Genetics, Erasmus University Medical Center, Rotterdam, Netherlands; CECAD Forschungszentrum, Universität zu Köln, Köln, Germany.
Wilbert P VermeijDepartment of Molecular Genetics, Erasmus University Medical Center , Rotterdam , Netherlands.
Paul de VosTop Institute Food and Nutrition, Wageningen, Netherlands; University of Groningen, Groningen, Netherlands.
Jerry M WellsTop Institute Food and Nutrition, Wageningen, Netherlands; Host Microbe Interactomics, Wageningen University, Wageningen, Netherlands.
Pieter J M LeenenDepartment of Immunology, Erasmus University Medical Center , Rotterdam , Netherlands.
Claudio NicolettiGut Health and Food Safety, Institute of Food Research, Norwich, UK; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Rudi W HendriksDepartment of Pulmonary Medicine, Erasmus University Medical Center , Rotterdam , Netherlands.
Huub F J SavelkoulCell Biology and Immunology Group, Wageningen University, Wageningen, Netherlands; Top Institute Food and Nutrition, Wageningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although it is clear that probiotics improve intestinal barrier function, little is known about the effects of probiotics on the aging intestine. We investigated effects of 10-week bacterial supplementation of

Indexed as

agingimmunityintestinal barriermicrobiotamucusprobiotics

Identifiers

PMID27774093
PMCPMC5054004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.