ArticleFrontiers in human neuroscience2016
Pre-stimulus Alpha Oscillations and Inter-subject Variability of Motor Evoked Potentials in Single- and Paired-Pulse TMS Paradigms.
Article in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
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- Resting-state neural oscillations of the motor system influence the resting motor threshold.Scientific reports · 2026Observational
- AI-Driven Hemodynamic Detection of Self-Induced Daydreaming With EMG-Based Physiological Triggers During Pre- and Post-Prandial States Using fNIRS and EGG.CNS neuroscience & therapeutics · 2026Article
- Phase-dependent stimulation response is shaped by the brain's dynamic functional connectivity.Network neuroscience (Cambridge, Mass.) · 2026Article
- State-Dependent Transcranial Magnetic Stimulation Synchronized with Electroencephalography: Mechanisms, Applications, and Future Directions.Brain sciences · 2025Review
- Spatiotemporal dynamics of cortical somatosensory network in typically developing children.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Inter-Individual Variability in Motor Output Is Driven by Recruitment Gain in the Corticospinal Tract Rather Than Motor Threshold.Brain sciences · 2022Article
- Nonequivalent After-Effects of Alternating Current Stimulation on Motor Cortex Oscillation and Inhibition: Simulation and Experimental Study.Brain sciences · 2022Article
- Inhibitory and excitatory responses in the dorso-medial prefrontal cortex during threat processing.Frontiers in neuroscience · 2022Article
- Impact of operator experience on transcranial magnetic stimulation.Clinical neurophysiology practice · 2022Article
- The Effect of Sound and Stimulus Expectation on Transcranial Magnetic Stimulation-Elicited Motor Evoked Potentials.Brain topography · 2021Article
- Online and offline effects of transcranial alternating current stimulation of the primary motor cortex.Scientific reports · 2021Article
- The Corticospinal Excitability Can Be Predicted by Spontaneous Electroencephalography Oscillations.Frontiers in neuroscience · 2021Article
- Spontaneous Fluctuations in Oscillatory Brain State Cause Differences in Transcranial Magnetic Stimulation Effects Within and Between Individuals.Frontiers in human neuroscience · 2021Review
- Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics.Scientific reports · 2020Article
- Motor Cortex Inputs at the Optimum Phase of Beta Cortical Oscillations Undergo More Rapid and Less Variable Corticospinal Propagation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Pulsed Facilitation of Corticospinal Excitability by the Sensorimotor μ-Alpha Rhythm.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Predicting the Response to Non-invasive Brain Stimulation in Stroke.Frontiers in neurology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inter- and intra-subject variability of the motor evoked potentials (MEPs) to TMS is a well-known phenomenon. Although a possible link between this variability and ongoing brain oscillations was demonstrated, the results of the studies are not consistent with each other. Exploring this topic further is important since the modulation of MEPs provides unique possibility to relate oscillatory cortical phenomena to the state of the motor cortex probed with TMS. Given that alpha oscillations were shown to reflect cortical excitability, we hypothesized that their power and variability might explain the modulation of subject-specific MEPs to single- and paired-pulse TMS (spTMS, ppTMS, respectively). Neuronal activity was recorded with multichannel electroencephalogram. We used spTMS and two ppTMS conditions: intracortical facilitation (ICF) and short-interval intracortical inhibition (SICI). Spearman correlations were calculated within and across subjects between MEPs and the pre-stimulus power of alpha oscillations in low (8-10 Hz) and high (10-12 Hz) frequency bands. Coefficient of quartile variation was used to measure variability. Across-subject analysis revealed no difference in the pre-stimulus alpha power among the TMS conditions. However, the variability of high-alpha power in spTMS condition was larger than in the SICI condition. In ICF condition pre-stimulus high-alpha power variability correlated positively with MEP amplitude variability. No correlation has been observed between the pre-stimulus alpha power and MEP responses in any of the conditions. Our results show that the variability of the alpha oscillations can be more predictive of TMS effects than the commonly used power of oscillations and we provide further support for the dissociation of high and low-alpha bands in predicting responses produced by the stimulation of the motor cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.