Evidence map›Paper›PMID 27773996›Full record

ArticleClinical medicine insights. Circulatory, respiratory and pulmonary medicine2016

Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans.

Natalie E Taylor, Sarah E Baker, Thomas P Olson, Sophie Lalande, Bruce D Johnson, Eric M Snyder

Open access · goldAbstract read
In one paragraph

Article in Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Natalie E TaylorSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Sarah E BakerResearch Fellow, Department of Anesthesiology, Mayo Clinic, Rochester, MN, USA.
Thomas P OlsonAssistant Professor of Medicine, Consultant, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Sophie LalandeAssistant Professor, Department of Kinesiology, University of Toledo, OH, USA.
Bruce D JohnsonProfessor of Medicine and Physiology, Consultant, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Eric M SnyderAssistant Professor, School of Kinesiology, University of Minnesota, Minneapolis, MN, USA.
Mayo Clinic in Arizona · USUniversity of Minnesota · USUniversity of Toledo · USUniversity of Wisconsin–Madison · US

Funding

DIABETES AND METABOLISMT32DK007352 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1986 to 2026
$9.4M
Pulmonary Limitations in Chronic Heart FailureR01HL071478 · NHLBI · MAYO CLINIC ROCHESTER · PI JOHNSON, BRUCE D · 2002 to 2014
$3.7M
NHLBI NIH HHS R01 HL071478NIDDK NIH HHS T32 DK007352
6 · The paper itself

Abstract

backgroundBeta-2 adrenergic receptors (β

methodsWe assessed the diffusing capacity of the lungs for carbon monoxide (DLCO) and nitric oxide (DLNO) at baseline, 30 minutes, and 60 minutes following nebulized albuterol (2.5 mg, diluted in 3 mL normal saline) in 45 healthy subjects. Seventeen subjects repeated these measures following nebulized normal saline (age = 27 ± 9 years, height = 165 ± 21 cm, weight = 68 ± 12 kg, BMI = 26 ± 9 kg/m

resultsAlbuterol resulted in a decrease in SVR, and an increase in Q, FEV

conclusionThese data suggest that nebulized albuterol improves pulmonary function in healthy humans, while nebulization of both albuterol and saline results in an increase in DM/

Indexed as

CFTRlung diffusionlung fluidsodium channels

Identifiers

PMID27773996
PMCPMC5063752
OpenAlexW2530438291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.