Evidence map›Paper›PMID 27773567›Full record

ArticleCurrent biology : CB2016

Vision Drives Accurate Approach Behavior during Prey Capture in Laboratory Mice.

Jennifer L Hoy, Iryna Yavorska, Michael Wehr, Cristopher M Niell

Abstract read
In one paragraph

Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed.

  1. PSD-95 drives binocular vision maturation critical for predation.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026
    Review
  8. Article
  9. Article
  10. Predictive pursuit emerges in high-dimensional recurrent neural networks.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Connectivity, Computation, and Plasticity of the Early Visual System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  18. Article
  19. Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025
    Article
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jennifer L HoyInstitute of Neuroscience, University of Oregon, Eugene, OR 97403, USA; Department of Biology, University of Oregon, Eugene, OR 97403, USA.
Iryna YavorskaInstitute of Neuroscience, University of Oregon, Eugene, OR 97403, USA; Department of Psychology, University of Oregon, Eugene, OR 97403, USA.
Michael WehrInstitute of Neuroscience, University of Oregon, Eugene, OR 97403, USA; Department of Psychology, University of Oregon, Eugene, OR 97403, USA.
Cristopher M NiellInstitute of Neuroscience, University of Oregon, Eugene, OR 97403, USA; Department of Biology, University of Oregon, Eugene, OR 97403, USA. Electronic address: cniell@uoregon.edu.

Funding

Neural pathways and behavioral state in the visual systemR01EY023337 · NEI · UNIVERSITY OF OREGON · PI NIELL, CRISTOPHER M · 2013 to 2017
$1.8M
Synaptic mechanisms of coding transformations in auditory cortexR01DC011379 · NIDCD · UNIVERSITY OF OREGON · PI WEHR, MICHAEL · 2011 to 2015
$1.8M
Mechanisms of receptive field establishment in mouse visual cortexF32EY024179 · NEI · UNIVERSITY OF OREGON · PI HOY, JENNIFER LYN · 2014 to 2015
$109k
NEI NIH HHS F32 EY024179NEI NIH HHS R01 EY023337NIDCD NIH HHS R01 DC011379
6 · The paper itself

Abstract

The ability to genetically identify and manipulate neural circuits in the mouse is rapidly advancing our understanding of visual processing in the mammalian brain [1, 2]. However, studies investigating the circuitry that underlies complex ethologically relevant visual behaviors in the mouse have been primarily restricted to fear responses [3-5]. Here, we show that a laboratory strain of mouse (Mus musculus, C57BL/6J) robustly pursues, captures, and consumes live insect prey and that vision is necessary for mice to perform the accurate orienting and approach behaviors leading to capture. Specifically, we differentially perturbed visual or auditory input in mice and determined that visual input is required for accurate approach, allowing maintenance of bearing to within 11° of the target on average during pursuit. While mice were able to capture prey without vision, the accuracy of their approaches and capture rate dramatically declined. To better explore the contribution of vision to this behavior, we developed a simple assay that isolated visual cues and simplified analysis of the visually guided approach. Together, our results demonstrate that laboratory mice are capable of exhibiting dynamic and accurate visually guided approach behaviors and provide a means to estimate the visual features that drive behavior within an ethological context.

Indexed as

Predatory BehaviorVision, OcularVisual PerceptionAnimalsAuditory PerceptionFemaleMaleMiceMice, Inbred C57BLOrientationRandom Allocationbehaviorethologymouseprey capturevision

Identifiers

PMID27773567
PMCPMC5121011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.