ArticleCell host & microbe2016
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
Open access · hybridAbstract read
In one paragraph
Article in Cell host & microbe, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 326 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
326citing papers in PubMed, 1 pooled it
21.4field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
326 citing papers in PubMed, 1 synthesis or guideline pooled it, 494 citations in OpenAlex.
- The m6A epitranscriptome opens a new charter in immune system logic.Epigenetics · 2021Pooled it
- PRRSV suppresses FTO-dependentmBio · 2026Article
- Transcriptional architecture of African swine fever virus.PLoS pathogens · 2026Article
- Characterization of the virus-host RNA-RNA interactome across important human pathogenic RNA viruses.PLoS pathogens · 2026Article
- Investigation of TRMT61B methyltransferase activity on mRNA and its effects on translation.Nucleic acids research · 2026Article
- Poxvirus infection triggers remodeling of host m⁶A epitranscriptome and benefits from the m⁶A regulatory responses.Virology journal · 2026Article
- RNA modification-mediated multidimensional crosstalk: a novel perspective on gene expression regulation.Genome biology · 2026Review
- m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- mbioRxiv : the preprint server for biology · 2026Article
- N6-methyladenosine within transmissible gastroenteritis virus genomic RNA inhibits its replication via efficient recognition by RNA sensor RIG-I.Journal of virology · 2026Article
- The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover.Nucleic acids research · 2026Article
- m6A-Modified Nucleotide Bases Improve Translation of In Vitro-Transcribed Chimeric Antigen Receptor (CAR) mRNA in T Cells.International journal of molecular sciences · 2026Article
- Potyviruses recruit host eIF4A3 to block m6A-mediated RNA decay by steric hindrance of viral RNA methylation in plants.Nucleic acids research · 2026Article
- The new era of single-molecule RNA modification detection through nanopore base-calling models.Nature reviews. Molecular cell biology · 2026Review
- Multidimensional mechanisms of SFTSV-host interactions: viral protein functions, mFrontiers in cellular and infection microbiology · 2026Review
- N6-methyladenosine as a potential epitranscriptomic immune rheostat during SARS-CoV-2 infection.Frontiers in immunology · 2026Review
- Investigation of TRMT61B methyltransferase activity on mRNA and its effects on translation.bioRxiv : the preprint server for biology · 2025Article
- Regulation of viral hepatitis by N6-methyladenosine RNA methylation.Emerging microbes & infections · 2025Review
- SARS-CoV-2 and HCoV-OC43 regulate host m6A modification via activation of the mTORC1 signalling pathway to facilitate viral replication.Emerging microbes & infections · 2025Article
- Paramyxovirus matrix protein redirects METTL3 for dual regulation of viral replication and immune evasion.PLoS pathogens · 2025Article
266 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 9 institutions in 2 countries.
Nandan S GokhaleDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Alexa B R McIntyreDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10021, USA; Tri-Institutional Program in Computational Biology and Medicine, New York City, NY 10065, USA.
Michael J McFaddenDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Allison E RoderDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Edward M KennedyDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Jorge A GandaraDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10021, USA.
Sharon E HopcraftDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Kendra M QuickeDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Christine VazquezDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Jason WillerDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
Olga R IlkayevaDuke Molecular Physiology Institute, Duke University, Durham NC 27701, USA.
Brittany A LawDepartment of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Christopher L HolleyDepartment of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Mariano A Garcia-BlancoDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA; Programme in Emerging Infectious Disease, Duke-NUS Medical School, Singapore 169857, Singapore.
Matthew J EvansDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mehul S SutharDivision of Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Shelton S BradrickDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10021, USA; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: chm2042@med.cornell.edu.
Stacy M HornerDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: stacy.horner@duke.edu.
Duke Medical Center · USDuke University Hospital · USEmory University · USIcahn School of Medicine at Mount Sinai · USThe University of Texas Medical Branch at Galveston · USCornell University · USDuke University · USMIND Research Institute · USWeill Cornell Medicine · US
Funding
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5MWest Nile Virus and host control of innate defensesU19AI083019 · NIAID · UNIVERSITY OF WASHINGTON · PI CLARK, EDWARD A · 2009 to 2018
$22.5MTRAINING PROGRAM: MECHANISMS OF VIRUS-HOST INTERACTIONST32AI007647 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI Domenico Tortorella · 2000 to 2026
$11.5MLATE TRANSITION METAL CATALYSTS FOR ORGANIC SYNTHESISR01GM058160 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BUCHWALD, STEPHEN L · 1998 to 2016
$9.0MViral Oncology Training GrantT32CA009111 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH A. · 1985 to 2023
$8.9MEpigenome Interactions in Complex Neurogenetic DisordersR01NS076465 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD, ROSS, MARGARET ELIZABETH · 2011 to 2015
$5.8MDefining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycleR01AI125416 · NIAID · DUKE UNIVERSITY · PI Stacy Michelle Horner · 2016 to 2026
$5.5MTargeting dengue in the mosquito with small moleculesR01AI101431 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DIMOPOULOS, GEORGE, ENGEL, DANIEL A · 2012 to 2016
$4.3MDiscovery and development of broad spectrum anti-flaviviral drugsR01AI089526 · NIAID · DUKE UNIVERSITY · PI ENGEL, DANIEL A, GARCIA-BLANCO, MARIANO A. · 2010 to 2014
$4.1MStudy of Neural Tube Defects Etiology: Genome and ExposomeR01ES021006 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI FINNELL, RICHARD H., MASON, CHRISTOPHER EDWARD · 2012 to 2014
$1.0MSNORNAS ARE ESSENTIAL MEDIATORS OF ROS SIGNALING IN CARDIOVASCULAR CELLSK08HL114889 · NHLBI · WASHINGTON UNIVERSITY · PI HOLLEY, CHRISTOPHER LEE · 2012 to 2016
$614kCommunity Research Education and Engagement for Data Science (CREEDS)R25EB020393 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLAUDIO, LUZ, KOVATCH, PATRICIA · 2015 to 2017
$578kNCI NIH HHS T32 CA009111NHLBI NIH HHS K08 HL114889NIAID NIH HHS P30 AI064518NIAID NIH HHS R01 AI089526NIAID NIH HHS R01 AI101431NIAID NIH HHS R01 AI125416NIAID NIH HHS R21 AI129851NIAID NIH HHS R56 AI110516NIAID NIH HHS T32 AI007647NIAID NIH HHS U19 AI083019NIBIB NIH HHS R25 EB020393NIEHS NIH HHS R01 ES021006NIGMS NIH HHS R01 GM058160NINDS NIH HHS R01 NS076465
Abstract
The RNA modification N6-methyladenosine (m
Indexed as
Gene Expression Regulation, ViralHost-Pathogen InteractionsVirus ReplicationAdenosineFlaviviridaeMethyltransferasesOxidoreductases, N-DemethylatingRNA, ViralViral LoadAdenosineMethyltransferasesN-methyladenosineOxidoreductases, N-DemethylatingRNA, ViraldengueFlaviviridaeHCVm(6)AN6-methyladenosineRNA-modificationsviral particle productionWest Nileyellow feverZika
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.