Evidence map›Paper›PMID 27773422›Full record

ArticlePediatric neurology2016

Clinical Characteristics and Long-Term Outcomes of Movement Disorders in Childhood Thalamic Tumors.

Zsila S Sadighi, Jennifer Zabrowski, Frederick A Boop, Alberto Broniscer, Amar Gajjar, Raja B Khan

Abstract read
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In one paragraph

Article in Pediatric neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Hemidystonia secondary to pediatric thalamic glioblastoma: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  2. Thalamic tumors in children: case series from our institution and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Review
  3. Article
  4. Movement Disorders in Childhood Thalamic Tumors.Pediatric neurology briefs · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zsila S SadighiDivision of Neurology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address: zsila.sadighi@stjude.org.
Jennifer ZabrowskiDivision of Neurology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee.
Frederick A BoopDepartment of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, Tennessee; Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee; Division of Neurosurgery, St. Jude Children's Research Hospital, Memphis, Tennessee.
Alberto BroniscerDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Amar GajjarDivision of Neurology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Raja B KhanDivision of Neurology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee.
St. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe studied the outcomes of movement disorders that were associated with childhood thalamic tumors.

methodsWe retrospectively reviewed 83 children with thalamic tumors treated at our institution from 1996 to 2013 to document the incidence and outcome of movement disorders. Magnetic resonance imaging was used to analyze the involvement of thalamic nuclei, and three instruments were used to rate the severity of the disorders.

resultsNine (11%) patients had one or more of the following movement disorders: postural tremor, resting tremor, ballism, dystonia, myoclonus, and athetosis. Median age at tumor diagnosis was seven years (range, 0.25 to 11 years), and the average age at movement disorder onset was eight years (range, 1.5 to 11 years). Movement disorders developed at a median of 1.5 months (range, 0 to 4 months) after surgical resection. The severity of the disorders was either unchanged or slightly improved during follow-up. The red nuclei were the only thalamic structures that showed tumor involvement in all nine patients.

conclusionsNo specific injury of the thalamic nuclei was associated with movement disorders in children with thalamic tumors, and the severity of these disorders did not change over time.

Indexed as

Brain NeoplasmsChildChild, PreschoolFemaleHumansInfantMaleMovement DisordersRetrospective StudiesThalamusTime FactorsTreatment Outcomechildhoodmovement disorderoutcomethalamic tumors

Identifiers

PMID27773422
OpenAlexW2508983733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.