Evidence map›Paper›PMID 27771980›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2017

The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration.

Gabriel A Knudsen, J Michael Sanders, Michael F Hughes, Ethan P Hull, Linda S Birnbaum

Abstract read
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. 2,4,6-Tribromophenol Disposition and Kinetics in Rodents: Effects of Dose, Route, Sex, and Species.Toxicological sciences : an official journal of the Society of Toxicology · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gabriel A Knudsena NCI Laboratory of Toxicology and Toxicokinetics , Research Triangle Park , NC , USA and.
J Michael Sandersa NCI Laboratory of Toxicology and Toxicokinetics , Research Triangle Park , NC , USA and.
Michael F Hughesb Integrated Systems Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency , Research Triangle Park , NC , USA.
Ethan P Hulla NCI Laboratory of Toxicology and Toxicokinetics , Research Triangle Park , NC , USA and.
Linda S Birnbauma NCI Laboratory of Toxicology and Toxicokinetics , Research Triangle Park , NC , USA and.
Research Triangle Park Foundation · USEnvironmental Protection Agency · US

Funding

Studies of the fate of environmental contaminants in humans and animalsZIABC011476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BIRNBAUM, LINDA · 2013 to 2019
$5.8M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC011476
6 · The paper itself

Abstract

1. It was important to investigate the disposition of decabromodiphenyl ethane (DBDPE) based on concerns over its structural similarities to decabromodiphenyl ether (decaBDE), high potential for environmental persistence and bioaccumulation, and high production volume. 2. In the present study, female Sprague Dawley rats were administered a single dose of [

Indexed as

Administration, IntravenousAdministration, OralAnimalsBromobenzenesFemaleFlame RetardantsHumansMaleMiceRatsRats, Sprague-DawleySkinBromobenzenesdecabromodiphenyl ethaneFlame RetardantsADMEbioaccumulationbrominated flame retardantlipophilicpersistent organic pollutant

Identifiers

PMID27771980
PMCPMC5463998
OpenAlexW2538756124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.