Evidence map›Paper›PMID 27771883›Full record

ReviewMycopathologia2017

Natural Products: An Alternative to Conventional Therapy for Dermatophytosis?

Graciliana Lopes, Eugénia Pinto, Lígia Salgueiro

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Multifunctional Activity ofPlants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Caffeine Protects Keratinocytes fromInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Heliyon · 2023
    Article
  11. Antifungal activity ofCurrent medical mycology · 2023
    Article
  12. Article
  13. Potential inhibitory activity of phytoconstituents against black fungus:Computational toxicology (Amsterdam, Netherlands) · 2022
    Article
  14. Antifungal Activity of Amphiphilic Perylene Bisimides.Molecules (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Isoflavaspidic Acid PB Extracted fromBioMed research international · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Graciliana LopesCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Rua dos Bragas 289, 4050-123, Porto, Portugal.
Eugénia PintoCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Rua dos Bragas 289, 4050-123, Porto, Portugal. epinto@ff.up.pt.ORCID http://orcid.org/0000-0003-2948-5809
Lígia SalgueiroCNC.IBILI/Faculty of Pharmacy, University of Coimbra, Azinhaga de S. Comba, 3000-354, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased incidence of fungal infections, associated with the widespread use of antifungal drugs, has resulted in the development of resistance, making it necessary to discover new therapeutic alternatives. Among fungal infections, dermatophytoses constitute a serious public health problem, affecting 20-25 % of the world population. Medicinal plants represent an endless source of bioactive molecules, and their volatile and non-volatile extracts are clearly recognized for being the historical basis of therapeutic health care. Because of this, the research on natural products with antifungal activity against dermatophytes has considerably increased in recent years. However, despite the recognized anti-dermatophytic potential of natural products, often advantageous face to commercial drugs, there is still a long way to go until their use in therapeutics. This review attempts to summarize the current status of anti-dermatophytic natural products, focusing on their mechanism of action, the developed pharmaceutical formulations and their effectiveness in human and animal models of infection.

Indexed as

AnimalsAntifungal AgentsArthrodermataceaeBiological ProductsDrug DiscoveryHumansPhytochemicalsPlant ExtractsPlantsTineaAntifungal AgentsBiological ProductsPhytochemicalsPlant ExtractsDermatophytosisEssential oilsNatural productsNon-volatile extracts

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.