Evidence map›Paper›PMID 27771829›Full record

ArticleClinical oral investigations2017

A retrospective study of osteomyelitis and osteonecrosis of the jaws and its etiologic implication of bisphosphonate in Asians.

Sung Ok Hong, Chae-Yoon Lee, Junho Jung, Deog-Yoon Kim, Christian Walter, Yong-Dae Kwon

Abstract read
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In one paragraph

Article in Clinical oral investigations, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Is teriparatide therapy effective for medication-related osteonecrosis of the jaw? A systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
  2. Article
  3. Frontiers in cellular and infection microbiology · 2022
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sung Ok HongDepartment of Dentistry (Oral & Maxillofacial Surgery), International St. Mary's Hospital, Catholic Kwandong University, Incheon, South Korea.
Chae-Yoon LeeDepartment of Oral & Maxillofacial Surgery, Graduate School, Kyung Hee University, Kyungheedaero 26, Seoul, 02447, South Korea.
Junho JungDepartment of Oral & Maxillofacial Surgery, Universitätsmedizin Mainz, Augustusplatz 2, Mainz, 55131, Germany.
Deog-Yoon KimDepartment of Nuclear Medicine, School of Medicine, Kyung Hee University, Kyungheedaero 26, Seoul, 02447, South Korea.
Christian WalterDepartment of Oral & Maxillofacial Surgery, Universitätsmedizin Mainz, Augustusplatz 2, Mainz, 55131, Germany.
Yong-Dae KwonDepartment of Oral & Maxillofacial Surgery, Center for Refractory Jawbone Diseases, School of Dentistry, Kyung Hee University, Kyungheedaero 26, Seoul, 02447, South Korea. yongdae.kwon@gmail.com.ORCID http://orcid.org/0000-0001-9620-4814
Kyung Hee University · KRJohannes Gutenberg University Mainz · DECatholic Kwandong University International St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study were to find the annual case trend of inflammatory jawbone diseases and to investigate the impact of medication-related osteonecrosis of the jaws (MRONJ). MATERIAL AND

methodsA retrospective study of 372 patients diagnosed with inflammatory jawbone condition except for alveolar osteitis from 2007 to 2015 was initiated. History taking and investigation of etiologic factors MRONJ, osteoradionecrosis (ORN), odontogenic infection, foreign body, and trauma were investigated. A separate analysis showed the number of MRONJ cases in two age groups (under 70 years; 70 years and over) and serum C-terminal peptide (s-CTX) values that were found.

resultsThe results showed that the number of MRONJ cases was significantly larger in the older age group (p < 0.05). Regarding gender and sites of lesions, MRONJ was significantly frequent in the female and the mandible (p < 0.05). The R

conclusionThe number of MRONJ has escalated, and most of the patients are elderly people. The current trend of inflammatory conditions of the jaw may have changed since the advent of MRONJ. CLINICAL RELEVANCE: Long-term bisphosphonate therapy became a major risk factor for the osteomyelitis and osteonecrosis of the jaws. Thorough medical history, taking would be essential and communication with prescribing physicians should be emphasized during the dental treatment planning.

Indexed as

AdolescentAdultAgedAged, 80 and overBisphosphonate-Associated Osteonecrosis of the JawChildFemaleHumansMaleMiddle AgedOsteomyelitisRepublic of KoreaRetrospective StudiesRisk FactorsBisphosphonatesInflammatory jawbone diseaseMRONJOsteoporosis

Identifiers

PMID27771829
OpenAlexW2537357516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.