Evidence map›Paper›PMID 27771364›Full record

ArticleMetabolic engineering2016

Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO

Andrew J Loder, Yejun Han, Aaron B Hawkins, Hong Lian, Gina L Lipscomb, Gerrit J Schut, Matthew W Keller, Michael W W Adams, Robert M Kelly

Open access · greenAbstract read
In one paragraph

Article in Metabolic engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Engineering the hyperthermophilic archaeonApplied and environmental microbiology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. (Frontiers in microbiology · 2021
    Article
  13. Article
  14. Biotechnology of extremely thermophilic archaea.FEMS microbiology reviews · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrew J LoderDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, United States.
Yejun HanDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, United States.
Aaron B HawkinsDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, United States.
Hong LianDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, United States.
Gina L LipscombDept. of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, United States.
Gerrit J SchutDept. of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, United States.
Matthew W KellerDept. of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, United States.
Michael W W AdamsDept. of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, United States.
Robert M KellyDepartment of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695-7905, United States. Electronic address: rmkelly@ncsu.edu.
North Carolina State University · USUniversity of Georgia · US

Funding

Molecular Biotechnology Training at North Carolina State UniversityT32GM008776 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KELLY, ROBERT M · 2000 to 2019
$3.9M
NIGMS NIH HHS T32 GM008776
6 · The paper itself

Abstract

The 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle fixes CO

Indexed as

Models, BiologicalArchaeaCarbon DioxideExtremophilesHydroxybutyratesKineticsLactic AcidMetabolic Clearance RateMetabolic Flux AnalysisMetabolic Networks and PathwaysSignal TransductionSulfolobaceae4-hydroxybutyric acidCarbon Dioxidehydracrylic acidHydroxybutyratesLactic Acid3-hydroxypropionate4-hydroxybutyrateCO(2) fixationMetallosphaera sedula

Identifiers

PMID27771364
PMCPMC5433351
OpenAlexW2536067108

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.