Evidence map›Paper›PMID 27771293›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2017

Utilizing the planarian voltage-gated ion channel transcriptome to resolve a role for a Ca

John D Chan, Dan Zhang, Xiaolong Liu, Magdalena Zarowiecki, Matthew Berriman, Jonathan S Marchant

Abstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. An insight into planarian regeneration.Cell proliferation · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Conserved biophysical features of the CaThe Journal of biological chemistry · 2020
    Article
  11. CaCold Spring Harbor perspectives in biology · 2019
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Dataset for aData in brief · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John D ChanDepartment of Pharmacology, University of Minnesota Medical School, MN 55455, United States.
Dan ZhangDepartment of Pharmacology, University of Minnesota Medical School, MN 55455, United States.
Xiaolong LiuDepartment of Pharmacology, University of Minnesota Medical School, MN 55455, United States.
Magdalena ZarowieckiParasite Genomics Group, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Matthew BerrimanParasite Genomics Group, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Jonathan S MarchantDepartment of Pharmacology, University of Minnesota Medical School, MN 55455, United States; The Stem Cell Institute, University of Minnesota Medical School, MN 55455, United States. Electronic address: march029@umn.edu.

Funding

Stem Cell Biology Training ProgramT32GM113846 · NIGMS · UNIVERSITY OF MINNESOTA · PI PERLINGEIRO, RITA C. R. · 2015 to 2019
$712k
Function and Chemotherapeutic Vulnerability of Flatworm Biogenic Amine ReceptorsF32AI124598 · NIAID · IOWA STATE UNIVERSITY · PI CHAN, JOHN D · 2017 to 2017
$59k
NIAID NIH HHS F32 AI124598NIGMS NIH HHS T32 GM113846Wellcome Trust
6 · The paper itself

Abstract

The robust regenerative capacity of planarian flatworms depends on the orchestration of signaling events from early wounding responses through the stem cell enacted differentiative outcomes that restore appropriate tissue types. Acute signaling events in excitable cells play an important role in determining regenerative polarity, rationalized by the discovery that sub-epidermal muscle cells express critical patterning genes known to control regenerative outcomes. These data imply a dual conductive (neuromuscular signaling) and instructive (anterior-posterior patterning) role for Ca

Indexed as

Ion Channel GatingTranscriptomeAnimalsCalcium ChannelsCalcium SignalingMusclesPlanariansCalcium ChannelsNeuromuscular signalingRegenerationTranscriptomeVoltage-operated Ca(2+) channels

Identifiers

PMID27771293
PMCPMC5397384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.