ArticleBMC public health2016
Racial disparities in adult all-cause and cause-specific mortality among us adults: mediating and moderating factors.
Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.
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Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Racial-Ethnic Disparities in Obesity and Biological, Behavioral, and Sociocultural Influences in the United States: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Healthy Weight and Cardiovascular Health Promotion Interventions for Adolescent and Young Adult Males of Color: A Systematic Review.American journal of men's health · 2018Pooled it
- Mitigating the health effects of systemic racism: Evaluation of the Race-Based Stress and Trauma Empowerment intervention.Contemporary clinical trials · 2023Trial
- Linking disease severity and mortality in obstructive sleep apnea: the role of the endothelial activation and stress index.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Historical slavery predicts contemporary disparities in mortality between Black and White Americans.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Attending an Historically Black College or University and all-cause mortality in US Black adults.American journal of epidemiology · 2026Article
- Article
- Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults.JACC. Advances · 2026Article
- The Mediating Effect of Socioeconomic Status and Persistent Poverty on Racial and Ethnic Disparities in Pediatric Cancer Mortality in the United States.Cancer medicine · 2026Article
- Telomere Length, Epigenetic Age Acceleration, and Mortality Risk in US Adult Populations: An Additive Bayesian Network Analysis.Aging cell · 2025Article
- Using machine-learning to identify differences in the association between blood-based biomarkers and later life health across race and ethnicity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Comparison of Racial and Ethnic Mortality Disparities among Post-9/11 Veterans with and without Traumatic Brain Injury to the Total U.S. Adult Population.Journal of racial and ethnic health disparities · 2025Article
- Plasma homocysteine level and trajectories in association with longitudinal increase in plasma neurofilament light among urban adults.GeroScience · 2025Article
- Associations of serial negative income shock and all-cause mortality: a longitudinal study in China.BMJ public health · 2024Article
- Plasma homocysteine and longitudinal change in cognitive function among urban adults.Journal of affective disorders · 2024Article
- Longitudinal association of homocysteine with depressive and anxiety symptoms among urban adults: healthy aging in neighborhoods of diversity across the life span study.Translational psychiatry · 2024Article
- Health and Community Care Workers' Knowledge and Perceptions of Social Prescribing in Singapore.Annals of geriatric medicine and research · 2024Article
- Association between social determinants of health and survival among the US cancer survivors population.BMC medicine · 2024Article
- Exploring the role of blood pressure in the black-white disparity in cardiovascular disease mortality: a causal mediation analysis.Journal of epidemiology and community health · 2024Article
- Serum neurofilament light chain as a prognostic marker of all-cause mortality in a national sample of US adults.European journal of epidemiology · 2024Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies uncovering factors beyond socio-economic status (SES) that would explain racial and ethnic disparities in mortality are scarce.
methodsUsing prospective cohort data from the Third National Health and Nutrition Examination Survey (NHANES III), we examined all-cause and cause-specific mortality disparities by race, mediation through key factors and moderation by age (20-49 vs. 50+), sex and poverty status. Cox proportional hazards, discrete-time hazards and competing risk regression models were conducted (N = 16,573 participants, n = 4207 deaths, Median time = 170 months (1-217 months)).
resultsAge, sex and poverty income ratio-adjusted hazard rates were higher among Non-Hispanic Blacks (NHBs) vs. Non-Hispanic Whites (NHW). Within the above-poverty young men stratum where this association was the strongest, the socio-demographic-adjusted HR = 2.59, p < 0.001 was only partially attenuated by SES and other factors (full model HR = 2.08, p = 0.003). Income, education, diet quality, allostatic load and self-rated health, were among key mediators explaining NHB vs. NHW disparity in mortality. The Hispanic paradox was observed consistently among women above poverty (young and old). NHBs had higher CVD-related mortality risk compared to NHW which was explained by factors beyond SES. Those factors did not explain excess risk among NHB for neoplasm-related death (fully adjusted HR = 1.41, 95 % CI: 1.02-2.75, p = 0.044). Moreover, those factors explained the lower risk of neoplasm-related death among MA compared to NHW, while CVD-related mortality risk became lower among MA compared to NHW upon multivariate adjustment.
conclusionsIn sum, racial/ethnic disparities in all-cause and cause-specific mortality (particularly cardiovascular and neoplasms) were partly explained by socio-demographic, SES, health-related and dietary factors, and differentially by age, sex and poverty strata.
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