ArticleeLife2016
Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 145 citations in OpenAlex.
- Insulin receptor signaling in gustatory cells suppresses sugar taste sensitivity and feeding iniScience · 2026Article
- Mating-Induced Behavioral Changes in FemaleInternational journal of molecular sciences · 2026Article
- Immobilization-free chemotaxis analysis reveals the novel behavioral mode of "leaving" inbioRxiv : the preprint server for biology · 2026Article
- Two neuropeptides that promote blood feeding ineLife · 2026Article
- Disentangling the reproductive and metabolic transcriptional responses to diet in Drosophila melanogaster.G3 (Bethesda, Md.) · 2026Article
- Ovary-Derived Signals Align Protein Appetite with Oogenesis.bioRxiv : the preprint server for biology · 2026Article
- Efficient planning and implementation of optimal foraging strategies under energetic constraints.PNAS nexus · 2026Article
- Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Sex-specific site preferences in response to resource value inBehavioral ecology and sociobiology · 2026Article
- Foraging as an ethological framework for neuroscience.Trends in neurosciences · 2025Review
- Connectomics Reveals a Feed-Forward Swallowing Circuit Driving Protein Appetite.bioRxiv : the preprint server for biology · 2025Article
- Extending homeostasis to thought dynamics for a comprehensive explanation of mind-wandering.Scientific reports · 2025Article
- Exploration-exploitation trade-off is regulated by metabolic state and taste value inbioRxiv : the preprint server for biology · 2024Article
- Fantastic beasts and how to study them: rethinking experimental animal behavior.The Journal of experimental biology · 2024Article
- Emergent spatial goals in an integrative model of the insect central complex.PLoS computational biology · 2023Article
- Mitonuclear interactions modulate nutritional preference.Biology letters · 2023Article
- Article
- Modulation and neural correlates of postmating sleep plasticity in Drosophila females.Current biology : CB · 2023Article
- Foraging and mating behaviors ofEcology and evolution · 2023Article
- Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Internal states can profoundly alter the behavior of animals. A quantitative understanding of the behavioral changes upon metabolic challenges is key to a mechanistic dissection of how animals maintain nutritional homeostasis. We used an automated video tracking setup to characterize how amino acid and reproductive states interact to shape exploitation and exploration decisions taken by adult
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.