Evidence map›Paper›PMID 27770470›Full record

ArticleHuman brain mapping2017

Altered interregional molecular associations of the serotonin transporter in attention deficit/hyperactivity disorder assessed with PET.

Thomas Vanicek, Alexandra Kutzelnigg, Cecile Philippe, Helen L Sigurdardottir, Gregory M James, Andreas Hahn, Georg S Kranz, Anna Höflich, Alexander Kautzky, Tatjana Traub-Weidinger and 5 more

Open access · greenAbstract read
In one paragraph

Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Cerebral serotonin transporter measurements with [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  8. Dopamine D1-Receptor Organization Contributes to Functional Brain Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. From metabolic connectivity to molecular connectivity: application to dopaminergic pathways.European journal of nuclear medicine and molecular imaging · 2020
    Article
  15. Making Sense of Connectivity.The international journal of neuropsychopharmacology · 2019
    Review
  16. Article
  17. [Research advances in pathogenesis of attention deficit hyperactivity disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Thomas VanicekDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Alexandra KutzelniggDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Cecile PhilippeDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Helen L SigurdardottirDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Gregory M JamesDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Andreas HahnDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Georg S KranzDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Anna HöflichDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Alexander KautzkyDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Tatjana Traub-WeidingerDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Marcus HackerDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Wolfgang WadsakDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Markus MitterhauserDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Austria.
Siegfried KasperDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Rupert LanzenbergerDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Austria.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Altered serotonergic neurotransmission has been found to cause impulsive and aggressive behavior, as well as increased motor activity, all exemplifying key symptoms of ADHD. The main objectives of this positron emission tomography (PET) study were to investigate the serotonin transporter binding potential (SERT BP

Indexed as

Positron-Emission TomographyAdultAttention Deficit Disorder with HyperactivityBrainCase-Control StudiesFemaleHumansLinear ModelsMalePsychiatric Status Rating ScalesSerotonin Plasma Membrane Transport ProteinsYoung AdultSerotonin Plasma Membrane Transport ProteinsADHDinterregional molecular associationsneuroimagingPETpositron emission tomographyserotoninSERT

Identifiers

PMID27770470
PMCPMC6867013
OpenAlexW2547185200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.