Evidence map›Paper›PMID 27770458›Full record

ArticleMagnetic resonance in medicine2017

Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.

Hong Shang, Subramaniam Sukumar, Cornelius von Morze, Robert A Bok, Irene Marco-Rius, Adam Kerr, Galen D Reed, Eugene Milshteyn, Michael A Ohliger, John Kurhanewicz and 3 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  5. Hyperpolarized Carbon-13 MRI in Breast Cancer.Diagnostics (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Fast Imaging for Hyperpolarized MR Metabolic Imaging.Journal of magnetic resonance imaging : JMRI · 2021
    Review
  11. Probing hepatic metabolism of [2-Magma (New York, N.Y.) · 2021
    Article
  12. Hyperpolarized Carbon (Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Simultaneous TJournal of magnetic resonance (San Diego, Calif. : 1997) · 2020
    Article
  18. Review
  19. Article
  20. Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarizedJournal of magnetic resonance (San Diego, Calif. : 1997) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hong ShangDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Subramaniam SukumarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Cornelius von MorzeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Robert A BokDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Irene Marco-RiusDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Adam KerrElectrical Engineering, Stanford University, Stanford, California, USA.
Galen D ReedHeartVista, Menlo Park, California, USA.
Eugene MilshteynDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Michael A OhligerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0003-4183-3634
John M PaulyElectrical Engineering, Stanford University, Stanford, California, USA.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.

Funding

TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Development and Translation of Hyperpolarized C-13 Prostate Cancer MRI MethodsR01EB017449 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KURHANEWICZ, JOHN, VIGNERON, DANIEL B · 2013 to 2017
$5.9M
Translating HP 13C MRI as a Novel Paradigm for Assessing Drug Target InhibitionR01CA183071 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HURD, RALPH EUGENE, MUNSTER, PAMELA N. · 2014 to 2018
$3.3M
New Instrumentation and Techniques for Hyperpolarized Metabolic and Perfusion MRIR01EB013427 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KURHANEWICZ, JOHN, VIGNERON, DANIEL B · 2013 to 2016
$2.8M
Molecular Imaging of Renal Transport and Metabolism using Hyperpolarized C-13 MRIK01DK099451 · NIDDK · WASHINGTON UNIVERSITY · PI VON MORZE, CORNELIUS · 2014 to 2018
$820k
NCI NIH HHS R01 CA183071NIBIB NIH HHS P41 EB013598NIBIB NIH HHS R01 EB013427NIBIB NIH HHS R01 EB017449NIDDK NIH HHS K01 DK099451
6 · The paper itself

Abstract

purposeBalanced steady-state free precession (bSSFP) sequences can provide superior signal-to-noise ratio efficiency for hyperpolarized (HP) carbon-13 ( THEORY AND

methodsThis novel approach for bSSFP spectral selectivity incorporates optimized short-duration spectrally selective radiofrequency pulses within a bSSFP pulse train and a carefully chosen repetition time to avoid banding artifacts.

resultsThe sequence enabled subsecond 3D dynamic spectrally selective imaging of

conclusionThis sequence is expected to benefit applications requiring dynamic volumetric imaging of metabolically active

Indexed as

AnimalsArtifactsCarbon IsotopesComputer SimulationImaging, Three-DimensionalLactatesMagnetic Resonance ImagingMicePhantoms, ImagingPyruvic AcidCarbon-13Carbon IsotopesLactatesPyruvic Acidbalanced SSFPbanding artifacthyperpolarized C-13optimized RF pulse designspectrally selective

Identifiers

PMID27770458
PMCPMC5400740

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.