ArticleThe Journal of pathology2017
Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia.
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Article in The Journal of pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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45citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
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45 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Phenotypic spectrum ofPeerJ · 2022Pooled it
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- Unraveling the SOX11-IGF2 signaling axis in early lung development: implications for lung disease.Communications biology · 2025Article
- Why some and not others? Understanding vascular phenotypes in genetic developmental lung diseases.Current opinion in pediatrics · 2025Review
- Decoding bronchopulmonary dysplasia in premature infants through an epigenetic lens.Frontiers in medicine · 2025Review
- Anti-CCL2 therapy reduces oxygen toxicity to the immature lung.Cell death discovery · 2024Article
- Conditional knockout of ITGB4 in bronchial epithelial cells directs bronchopulmonary dysplasia.Journal of cellular and molecular medicine · 2023Article
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- A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes.Cellular and molecular life sciences : CMLS · 2022Article
- Insights into the Black Box of Intra-Amniotic Infection and Its Impact on the Premature Lung: From Clinical and Preclinical Perspectives.International journal of molecular sciences · 2022Review
- TRAIL protects the immature lung from hyperoxic injury.Cell death & disease · 2022Article
- Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.International journal of molecular sciences · 2022Article
- When inflammation meets lung development-an update on the pathogenesis of bronchopulmonary dysplasia.Molecular and cellular pediatrics · 2022Review
- The Multifunctional Contribution of FGF Signaling to Cardiac Development, Homeostasis, Disease and Repair.Frontiers in cell and developmental biology · 2021Review
- rhKGF-2 Attenuates Smoke Inhalation Lung Injury of RatsFrontiers in pharmacology · 2021Article
- Cross-Talk Between Inflammation and Fibroblast Growth Factor 10 During Organogenesis and Pathogenesis: Lessons Learnt From the Lung and Other Organs.Frontiers in cell and developmental biology · 2021Review
- Hyperoxia and Lungs: What We Have Learned From Animal Models.Frontiers in medicine · 2021Review
Corrections and comments
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Authors and funding
25 authors at 7 institutions in 3 countries.
Cho-Ming ChaoUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Faady YahyaUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Alena MoiseenkoUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Caterina TiozzoDivision of Neonatology, Department of Pediatrics, Columbia University, New York, NY, USA.
Amit ShresthaUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Negah AhmadvandUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Elie El AghaUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Jennifer QuantiusUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Salma DilaiUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Vahid KheirollahiUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Matthew JonesUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Jochen WilhemUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Gianni CarraroDepartments of Medicine and Biomedical Sciences, Lung and Regenerative Medicine Institutes, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Harald EhrhardtUniversity Children's Hospital Gießen, Division of General Pediatrics and Neonatology, Justus-Liebig-University, Member of the German Lung Center (DZL), Gießen, Germany.
Klaus-Peter ZimmerUniversity Children's Hospital Gießen, Division of General Pediatrics and Neonatology, Justus-Liebig-University, Member of the German Lung Center (DZL), Gießen, Germany.
Guillermo BarretoLOEWE Research Group, Lung Cancer Epigenetic, Max Planck Institute for Heart and Lung Research, Member of the German Lung Center (DZL), 61231, Bad Nauheim, Germany.
Katrin AhlbrechtDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Member of the German Lung Center (DZL), 61231, Bad Nauheim, Germany.
Rory E MortyDepartment of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Member of the German Lung Center (DZL), 61231, Bad Nauheim, Germany.
Susanne HeroldUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Rosanna G AbellarDepartment of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA.
Werner SeegerUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Ralph SchermulyUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
Jin-San ZhangCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou, Zhejiang, 325027, PR China.
Parviz MinooDepartment of Pediatrics, Division of Newborn Medicine, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, 90027, USA.
Saverio BellusciUniversities of Giessen and Marburg Lung Center (UGMLC), Excellence Cluster Cardio-Pulmonary System (ECCPS), Member of the German Center for Lung Research (DZL), Department of Internal Medicine II, Aulweg 130, 35392, Giessen, Germany.
German Center for Lung Research · DEUniversities of Giessen and Marburg Lung Center · DEMax Planck Institute for Heart and Lung Research · DEColumbia University · USCedars-Sinai Medical Center · USChildren's Hospital of Los Angeles · USWenzhou University · CN
Funding
THE BIOLOGY OF PULMONARY ALVEOLAR FORMATIONR01HL122764 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MINOO, PARVIZ MINOO · 2015 to 2018
$1.6MMECHANISMS OF BPD PATHOGENESISR01HL107307 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MINOO, PARVIZ MINOO · 2012 to 2015
$1.6MNHLBI NIH HHS R01 HL107307NHLBI NIH HHS R01 HL122764
Abstract
Inflammation-induced FGF10 protein deficiency is associated with bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely born infants characterized by arrested alveolar development. So far, experimental evidence for a direct role of FGF10 in lung disease is lacking. Using the hyperoxia-induced neonatal lung injury as a mouse model of BPD, the impact of Fgf10 deficiency in Fgf10
Indexed as
AnimalsAnimals, NewbornBronchopulmonary DysplasiaCells, CulturedDisease Models, AnimalFemaleFibroblast Growth Factor 10Gene Expression RegulationHyperoxiaMaleMice, Inbred C57BLMice, TransgenicPulmonary SurfactantsReceptor, Fibroblast Growth Factor, Type 2RNA, MessengerFgf10 protein, mouseFibroblast Growth Factor 10Pulmonary SurfactantsReceptor, Fibroblast Growth Factor, Type 2RNA, MessengerAECIIbronchopulmonary dysplasiadifferentiationfibroblast growth factor 10surfactant
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