Evidence map›Paper›PMID 27770376›Full record

ArticleDigestive diseases and sciences2016

Endoscopic Submucosal Dissection of Superficial Esophageal Neoplasms Is Feasible and Not Riskier for Patients with Liver Cirrhosis.

Yung-Kuan Tsou, Chia-Yuan Liu, Kuang-I Fu, Cheng-Hui Lin, Mu-Shien Lee, Ming-Yao Su, Ken Ohata, Cheng-Tang Chiu

Abstract read
In one paragraph

Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Observational
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  8. Variceal ligation in decompensated cirrhosis before esophageal endoscopic submucosal dissection.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022
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  12. Water-pocket endoscopic submucosal dissection of an early esophageal adenocarcinoma in a patient with portal hypertension and varices.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2020
    Article
  13. Article
  14. Endoscopic submucosal dissection for Barrett's-associated adenocarcinoma in a patient with decompensated cirrhosis and esophageal varices.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yung-Kuan TsouDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chia-Yuan LiuDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital and Department of Medicine, Mackay Medical College, New Taipei, Taiwan.
Kuang-I FuDepartment of Gastroenterology, Kanma Memorial Hospital, Nasushiobara, Japan.
Cheng-Hui LinDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Mu-Shien LeeDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ming-Yao SuDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ken OhataDepartment of Gastroenterology, NTT Medical Center Tokyo, 5-9-22 Higashi-gotanda, Shinagawa-ku, Tokyo, 141-8625, Japan. ken.ohata1974@gmail.com.
Cheng-Tang ChiuDepartment of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal endoscopic submucosal dissection (ESD) has rarely been reported for the treatment of cirrhotic patients.

aimTo report the results of ESD treatment of superficial esophageal neoplasms (SENs) for cirrhotic patients.

methodsForty patients with 50 consecutive SENs undergoing 46 sessions of ESD were retrospectively reviewed. The cirrhotic group included eight patients (11 SENs) with liver cirrhosis consisting of six patients classified as Child-Pugh class A liver cirrhosis and two patients classified as class B liver cirrhosis. Four patients (6 SENs) had coexisting esophageal varices. Parameters were compared between the cirrhotic patients and the non-cirrhotic controls (32 patients, 39 SENs).

resultsPlatelet counts of the cirrhotic group were significantly lower, while international normalized ratio was significantly higher. When the cirrhotic group and non-cirrhotic group were compared, the mean tumor length (4 vs. 3.7 cm, p = 0.56) and median procedure time (15.1 vs. 11.5 min/cm

conclusionEsophageal ESD seems to be safely and can be effectively performed on cirrhotic patients, particularly those without severe liver dysfunction.

Indexed as

AdultAgedBlood Loss, SurgicalCarcinoma, Squamous CellCase-Control StudiesEndoscopic Mucosal ResectionEndosonographyEsophageal and Gastric VaricesEsophageal NeoplasmsEsophageal PerforationEsophageal Squamous Cell CarcinomaEsophagoscopyFemaleHumansInternational Normalized RatioLiver CirrhosisEndoscopic submucosal dissectionEsophageal varicesEsophagusLiver cirrhosisSuperficial esophageal neoplasm

Identifiers

PMID27770376
PMCPMC5104793

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.