Evidence map›Paper›PMID 27770290›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Minimally Invasive Resection of Adrenocortical Carcinoma: a Multi-Institutional Study of 201 Patients.

Christina W Lee, Ahmed I Salem, David F Schneider, Glen E Leverson, Thuy B Tran, George A Poultsides, Lauren M Postlewait, Shishir K Maithel, Tracy S Wang, Ioannis Hatzaras and 18 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

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  11. Minimally invasive adrenalectomy for adrenocortical cancers: A systematic review.Indian journal of urology : IJU : journal of the Urological Society of India
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 13 institutions in 1 country.

Christina W LeeDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, H4/730 Clinical Science Center, Madison, WI, 53792, USA.
Ahmed I SalemDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, H4/730 Clinical Science Center, Madison, WI, 53792, USA.
David F SchneiderDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, H4/730 Clinical Science Center, Madison, WI, 53792, USA.
Glen E LeversonDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, H4/730 Clinical Science Center, Madison, WI, 53792, USA.
Thuy B TranDepartment of Surgery, Stanford University, Palo Alto, CA, USA.
George A PoultsidesDepartment of Surgery, Stanford University, Palo Alto, CA, USA.
Lauren M PostlewaitDepartment of Surgery, Emory University School of Medicine, Atlanta, GA, USA.
Shishir K MaithelDepartment of Surgery, Stanford University, Palo Alto, CA, USA.
Tracy S WangDepartment of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Ioannis HatzarasDepartment of Surgery, New York University School of Medicine, New York, NY, USA.
Rivfka ShenoyDepartment of Surgery, New York University School of Medicine, New York, NY, USA.
John E PhayDepartment of Surgery, Ohio State University, Columbus, OH, USA.
Lawrence ShirleyDepartment of Surgery, Ohio State University, Columbus, OH, USA.
Ryan C FieldsDepartment of Surgery, Washington University, St. Louis, MO, USA.
Linda X JinDepartment of Surgery, Washington University, St. Louis, MO, USA.
Timothy M PawlikDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jason D PrescottDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jason K SicklickDepartment of Surgery, University of California, San Diego, CA, USA.
Shady GadDepartment of Surgery, University of California, San Diego, CA, USA.
Adam C YoppDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
John C MansourDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Quan-Yang DuhDepartment of Surgery, University of California, San Francisco, CA, USA.
Natalie SeiserDepartment of Surgery, University of California, San Francisco, CA, USA.
Carmen C SolorzanoDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Colleen M KiernanDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Konstantinos I VotanopoulosDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Edward A LevineDepartment of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Sharon M WeberDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, H4/730 Clinical Science Center, Madison, WI, 53792, USA. webers@surgery.wisc.edu.
University of Wisconsin–Madison · USStanford University · USJohns Hopkins University · USNew York University · USThe Ohio State University · USThe University of Texas Southwestern Medical Center · USUniversity of California, San Diego · USUniversity of California, San Francisco · USVanderbilt University Medical Center · USWake Forest University · USWashington University in St. Louis · USEmory University · USMedical College of Wisconsin · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Institutional Clinical and Translational Science AwardKL2TR000428 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$6.2M
Novel Allosteric Kinase Inhibitors Target Imatinib-Resistant GISTK08CA168999 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SICKLICK, JASON KEITH · 2014 to 2018
$888k
Defining the Germline Genomic Landscape of a Novel GIST Multi-tumor SyndromeR21CA192072 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SICKLICK, JASON KEITH · 2016 to 2017
$399k
NCATS NIH HHS KL2 TR000428NCATS NIH HHS UL1 TR000427NCI NIH HHS K08 CA168999NCI NIH HHS R21 CA192072
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMinimally invasive surgery for adrenocortical carcinoma (ACC) is controversial. We sought to evaluate the perioperative and long-term outcomes following minimally invasive (MIS) and open resection (OA) of ACC in patients treated with curative intent surgery.

methodsRetrospective data from patients who underwent adrenalectomy for primary ACC at 13 tertiary care cancer centers were analyzed, including demographics, clinicopathological, and operative outcomes. Outcomes following MIS were compared to OA.

resultsA total of 201 patients were evaluated including 47 MIS and 154 OA. There was no difference in utilization of MIS approach among institutions (p = 0.24) or 30-day morbidity (29.3 %, MIS, vs. 30.9 %, OA; p = 0.839). The only preoperatively determined predictor for MIS was smaller tumor size (p < 0.001). There was no difference in rates of intraoperative tumor rupture (p = 0.612) or R0 resection (p = 0.953). Only EBL (p = 0.038) and T stage (p = 0.045) were independent prognostic indicators of overall survival after adjusting for significant factors. The surgical approach was not associated with overall or disease-free survival.

conclusionMIS adrenalectomy may be utilized for preoperatively determined ACC ≤ 10.0 cm; however, OA should be utilized for adrenal masses with either preoperative or intraoperative evidence of local invasion or enlarged lymph nodes, regardless of size.

Indexed as

AdrenalectomyMinimally Invasive Surgical ProceduresAdrenal Cortex NeoplasmsAdrenocortical CarcinomaAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateYoung AdultAdrenocortical carcinomaDisease-free survivalMinimally invasive surgerySurgical approachSurvival

Identifiers

PMID27770290
PMCPMC5263186
OpenAlexW2532072886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.