Evidence map›Paper›PMID 27770215›Full record

ArticleAIDS and behavior2017

Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men.

George J Greene, Greg Swann, Angela J Fought, Alex Carballo-Diéguez, Thomas J Hope, Patrick F Kiser, Brian Mustanski, Richard T D'Aquila

Abstract read
In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 5 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 5 syntheses or guidelines pooled it, 131 citations in OpenAlex.

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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

George J GreeneDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Greg SwannDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Angela J FoughtDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Alex Carballo-DiéguezNew York State Psychiatric Institute and Columbia University Medical Center, New York, NY, USA.
Thomas J HopeDepartment of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Patrick F KiserDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Brian MustanskiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Richard T D'AquilaDepartment of Medicine (Infectious Diseases), HIV Translational Research Center, and Third Coast Center for AIDS Research, Northwestern University Feinberg School of Medicine, Arthur J. Rubloff Building, 750 N. Lake Shore Dr., Room 9-915, Chicago, IL, USA. richard.daquila@northwestern.edu.
Northwestern University · USColumbia University Irving Medical Center · USJohns Hopkins University Center for AIDS Research

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael E Newcomb · 2015 to 2026
$38.4M
Sustained Long Acting Prevention Against HIV Program OperationUM1AI120184 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOPE, THOMAS, KISER, PATRICK FRANKLIN · 2015 to 2019
$17.9M
NIAID NIH HHS P30 AI117943NIAID NIH HHS UM1 AI120184NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

HIV prevention method preferences were evaluated among 512 U.S. men who have sex with men (MSM; median age: 22 years). Approximately 90 % consistently preferred one option across pairwise comparisons of condoms, daily oral pre-exposure prophylaxis (PrEP), and long-acting PrEP delivered via either an injectable or one of two types of PrEP implants differing in visibility. Condoms were most frequently preferred (33.8 %), followed by non-visible implants (21.5 %), and oral PrEP (17.0 %); HIV risk was reported by more choosing implants. In a follow-up question comparing the four PrEP options only, daily oral pills and non-visible implants were most frequently preferred (35.5 and 34.3 %, respectively), followed by injections (25.2 %) and visible implants (4.3 %). An inductive, open-coding approach determined that convenience, duration of protection, and privacy were the most commonly cited reasons for a PrEP method choice, and associated with self-report of HIV risk. Tailoring PrEP product development to privacy and other concerns important to those at highest HIV risk may improve HIV prevention.

Indexed as

Administration, OralAdultCondomsHIV InfectionsHomosexuality, MaleHumansInjectionsMalePatient Acceptance of Health CarePre-Exposure ProphylaxisSexual and Gender MinoritiesYoung AdultHIVHomosexualityMalePre-exposure prophylaxisPreventionSexual behavior

Identifiers

PMID27770215
PMCPMC5380480
OpenAlexW2538443107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.