Evidence map›Paper›PMID 27770209›Full record

ArticleSurgery today2017

Current status of prophylactic surgical treatment for familial adenomatous polyposis in Japan.

Masato Yamadera, Hideki Ueno, Hirotoshi Kobayashi, Tsuyoshi Konishi, Fumio Ishida, Tatsuro Yamaguchi, Takao Hinoi, Yasuhiro Inoue, Yukihide Kanemitsu, Naohiro Tomita and 2 more

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Article in Surgery today, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Masato YamaderaDepartment of Surgery, National Defense Medical College, Saitama, Japan.
Hideki UenoDepartment of Surgery, National Defense Medical College, Saitama, Japan. ueno_surg1@ndmc.ac.jp.
Hirotoshi KobayashiCenter for Minimally Invasive Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Tsuyoshi KonishiGastroenterological Center, Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Fumio IshidaDigestive Disease Center, Showa University Northern Yokohama Hospital, Kanagawa, Japan.
Tatsuro YamaguchiDepartment of Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Takao HinoiDepartment of Gastroenterological and Transplant Surgery Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yasuhiro InoueDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Mie, Japan.
Yukihide KanemitsuDivision of Colorectal Surgery, National Cancer Center Hospital, Tokyo, Japan.
Naohiro TomitaDepartment of Surgery, Hyogo College of Medicine, Hyogo, Japan.
Hideyuki IshidaDepartment of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Kenichi SugiharaDepartment of Surgical Oncology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
National Defense Medical College · JPTokyo Medical and Dental University · JPHiroshima University · JPHyogo Medical University · JPJapanese Foundation For Cancer Research · JPMie University · JPSaitama Medical University · JPShowa University Northern Yokohama Hospital · JPTokyo Metropolitan Komagome Hospital · JPTokyo National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe conducted this study to clarify the current clinical practice of prophylactic colectomy for patients with familial adenomatous polyposis (FAP) in Japan.

methodsThis retrospective multi-center cohort study involved 23 specialized institutions for colorectal disease in Japan. We analyzed the records of 147 patients who underwent prophylactic surgical treatment between 2000 and 2012. Patients were divided into Group 1 (2000-2006) and Group 2 (2007-2012) based on their date of surgery.

resultsAge at the time of prophylactic surgery was 27 and 31 years in Groups 1 and 2, respectively. The proportion of attenuated FAP was significantly lower in Group 2 than in Group 1 (1.0 vs. 13 %, respectively). Pathological examination revealed an increased incidence of malignant polyps in the resected specimens from Group 2 patients (10 vs. 23 %, respectively; P = 0.034). Laparoscopic surgery was more frequent in Group 2 than in Group 1 (61 vs. 40 %, respectively). There was no surgical mortality in either group.

conclusionProphylactic surgery for FAP results in good short-term surgical outcomes in Japan. The current surgical approach is characterized by limited surgical indications for patients with attenuated FAP, delayed timing of colectomy, and the increasing standardization of laparoscopic surgery.

Indexed as

ColectomyProphylactic Surgical ProceduresAdenomatous Polyposis ColiAdolescentAdultAgedChildCohort StudiesFemaleHumansIncidenceJapanLaparoscopyMaleMiddle AgedMulticenter Studies as TopicFamilial adenomatous polyposisHereditary colorectal cancerProctocolectomyProphylactic surgeryTotal colectomy

Identifiers

PMID27770209
OpenAlexW2536366618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.