Evidence map›Paper›PMID 27770143›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2017

Raj Kumar Sharma, Kumudesh Mishra, Alvina Farooqui, Anu Behari, Vinay Kumar Kapoor, Neeraj Sinha

Abstract read
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In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. How I Manage My Patients with Gall Bladder Cancer?Indian journal of surgical oncology · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Gallbladder cancer: Progress in the Indian subcontinent.World journal of clinical oncology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Raj Kumar SharmaCentre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014, India.
Kumudesh MishraDepartment of Surgical Gastroenterology, SGPGIMS, Lucknow, 226014, India.
Alvina FarooquiDepartment of Biosciences, Integral University, Kursi Road, Lucknow, 226026, India.
Anu BehariDepartment of Surgical Gastroenterology, SGPGIMS, Lucknow, 226014, India.
Vinay Kumar KapoorDepartment of Surgical Gastroenterology, SGPGIMS, Lucknow, 226014, India.
Neeraj SinhaCentre of Biomedical Research, SGPGIMS Campus, Lucknow, 226014, India. neerajcbmr@gmail.com.
Sanjay Gandhi Post Graduate Institute of Medical Sciences · INIntegral University · INCentre of Biomedical Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OBJECTIVE AND

designWe present in this article MATERIAL/

methodsTotal of 71 human serum samples was divided into two groups, (n = 41, CC) and (n = 30 control).

resultsSerum metabolites such as glutamine, low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), alanine, branch chained amino acids (BCAA), histidine and tyrosine were found to be depleted whereas formate, lactate, 1,2-propanediol were found to be elevated in CC. Metabolic pathways associated with metabolite alteration have also been reported.

conclusionsNMR has been established for disease diagnosis along with identification of metabolic pattern recognition in biofluids. Gallstones cause inflammation of the gallbladder in the form of CC. Inflammation plays a major role in causation of gall bladder cancer and leads the way to malignancy. Metabolic analysis of CC may lead to early diagnosis of disease and its progression to gallbladder cancer.

Indexed as

MetabolomicsBiomarkersCholecystitisFormatesGlutamic AcidHistidineHumansLactic AcidLipoproteinsPropylene GlycolsProton Magnetic Resonance SpectroscopyBiomarkersFormatesformic acidGlutamic AcidHistidineLactic AcidLipoproteinsPropylene Glycols1H NMRChronic cholecystitisGallstone diseasePLS-DASerum metabolomics

Identifiers

PMID27770143
OpenAlexW2535607217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.