Evidence map›Paper›PMID 27769718›Full record

ReviewJournal of molecular biology2017

Choose Your Own Adventure: The Role of Histone Modifications in Yeast Cell Fate.

Deepika Jaiswal, Rashi Turniansky, Erin M Green

Abstract readReview
In one paragraph

Review in Journal of molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Alterations to the yeast chromatin landscape during hypoxia.bioRxiv : the preprint server for biology · 2026
    Article
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  11. The Roles of Chromatin Accessibility in Regulating theJournal of fungi (Basel, Switzerland) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deepika JaiswalDepartment of Biological Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address: deej@umbc.edu.
Rashi TurnianskyDepartment of Biological Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address: iu26299@umbc.edu.
Erin M GreenDepartment of Biological Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address: egreen@umbc.edu.

Funding

Mechanisms of chromatin homeostasis at telomeres mediated by histone lysine methyltransferasesR03AG052018 · NIA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI GREEN, ERIN · 2016 to 2016
$70k
NIA NIH HHS R03 AG052018
6 · The paper itself

Abstract

When yeast cells are challenged by a fluctuating environment, signaling networks activate differentiation programs that promote their individual or collective survival. These programs include the initiation of meiotic sporulation, the formation of filamentous growth structures, and the activation of programmed cell death pathways. The establishment and maintenance of these distinct cell fates are driven by massive gene expression programs that promote the necessary changes in morphology and physiology. While these genomic reprogramming events depend on a specialized network of transcription factors, a diverse set of chromatin regulators, including histone-modifying enzymes, chromatin remodelers, and histone variants, also play essential roles. Here, we review the broad functions of histone modifications in initiating cell fate transitions, with particular focus on their contribution to the control of expression of key genes required for the differentiation programs and chromatin reorganization that accompanies these cell fates.

Indexed as

Adaptation, PhysiologicalGene Expression Regulation, FungalHistone CodeHistonesSaccharomyces cerevisiaeHistoneschromatinmeiosispost-translational modificationsprogrammed cell deathpseudohyphal growth

Identifiers

PMID27769718
PMCPMC5395361

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.