Evidence map›Paper›PMID 27769584›Full record

Observational studyOphthalmology2016

Cataract Surgery in Children from Birth to Less than 13 Years of Age: Baseline Characteristics of the Cohort.

Michael X Repka, Trevano W Dean, Elizabeth L Lazar, Kimberly G Yen, Phoebe D Lenhart, Sharon F Freedman, Denise Hug, Bahram Rahmani, Serena X Wang, Raymond T Kraker and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Correction of aphakia using biometry-based contact lens calculation in pediatric cataract extraction: introducing the aphakic contact lens formula.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Article
  3. Ophthalmic outcomes five years after lensectomy among children with Down syndrome.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. [Glaucoma in infancy and childhood].Die Ophthalmologie · 2023
    Article
  10. Treatment of congenital and early childhood cataract.Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Review
  11. Observational
  12. Review
  13. [Treatment of congenital and early childhood cataract].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Michael X RepkaWilmer Institute, Baltimore, Maryland. Electronic address: pedig@jaeb.org.
Trevano W DeanJaeb Center for Health Research, Tampa, Florida.
Elizabeth L LazarJaeb Center for Health Research, Tampa, Florida.
Kimberly G YenBaylor College of Medicine/Texas Children's Hospital, Houston, Texas.
Phoebe D LenhartThe Emory Eye Center, Atlanta, Georgia.
Sharon F FreedmanDuke Eye Center, Durham, North Carolina.
Denise HugChildren's Mercy Hospitals and Clinics, Kansas City, Missouri.
Bahram RahmaniAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Serena X WangUniversity of Texas Southwestern, Dallas, Texas.
Raymond T KrakerJaeb Center for Health Research, Tampa, Florida.
David K WallaceDuke Eye Center, Durham, North Carolina.
Pediatric Eye Disease Investigator Group
Jaeb Center for Health Research · USBaylor College of Medicine · USChildren's Mercy Hospital · USEmory Eye Center · USLurie Children's Hospital · USMaryland Medical Research Institute · USThe University of Texas Southwestern Medical Center · US

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Pediatric Eye Disease Investigator Group: Chair's OfficeU10EY018810 · NEI · MAYO CLINIC ROCHESTER · PI HOLMES, JONATHAN M · 2009 to 2013
$3.5M
PEDIATRIC EYE DISEASE INVESTIGATOR GROUP: CHAIR'S OFFICEU10EY023198 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI WALLACE, DAVID K · 2014 to 2018
$1.4M
NEI NIH HHS U10 EY011751NEI NIH HHS U10 EY018810NEI NIH HHS U10 EY023198NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

objectiveTo describe baseline characteristics, initial postoperative refractive errors, operative complications, and magnitude of the intraocular lens (IOL) prediction error for refractive outcome in children undergoing lensectomy largely in North America.

designProspective registry study of children from birth to <13 years of age who underwent lensectomy for any reason within 45 days preceding enrollment.

participantsTotal of 1266 eyes of 994 children; 49% female and 59% white.

methodsMeasurement of refractive error, axial length, and complete ophthalmic examination.

main outcome measuresEye and systemic associated conditions, IOL style, refractive error, pseudophakic refraction prediction error, operative and perioperative complications.

resultsMean age at first eligible lens surgery was 4.2 years; 337 (34%) were <1 year of age. Unilateral surgery was performed in 584 children (59%). Additional ocular abnormalities were noted in 301 eyes (24%). An IOL was placed in 35 of 460 eyes (8%) when surgery was performed before 1 year of age, in 70 of 90 eyes (78%) from 1 to <2 years of age, and in 645 of 716 eyes (90%) from 2 to <13 years of age. The odds of IOL implantation were greater in children ≥2 years of age than in those <2 years of age (odds ratio = 29.1; P < 0.001; 95% confidence interval: 19.6-43.3). Intraoperative complications were reported for 69 eyes (5%), with the most common being unplanned posterior capsule rupture in 14 eyes, 10 of which had an IOL placed. Prediction error of the implanted IOL was <1.00 diopter in 54% of eyes, but >2.00 diopters in 15% of eyes.

conclusionsLensectomy surgery was performed throughout childhood, with about two-thirds of cases performed after 1 year of age. Initial surgery seemed safe, with a low complication rate. IOL placement was nearly universal in children 2 years of age and older. The immediate postoperative refraction was within 1 diopter of the target for about one-half of eyes.

Indexed as

AdolescentAphakia, PostcataractCataractCataract ExtractionChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornIntraoperative ComplicationsLens Implantation, IntraocularMaleNorth AmericaPostoperative Complications

Identifiers

PMID27769584
PMCPMC5121052
OpenAlexW2535425863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.