Evidence map›Paper›PMID 27769295›Full record

Trial reportJournal of health, population, and nutrition2016

A home calendar and recall method of last menstrual period for estimating gestational age in rural Bangladesh: a validation study.

Alison D Gernand, Rina Rani Paul, Barkat Ullah, Muhammad A Taher, Frank R Witter, Lee Wu, Alain B Labrique, Keith P West, Parul Christian

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in Journal of health, population, and nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00860470 (Antenatal Multiple Micronutrient Supplementation to Improve Infant Survival and Health in Bangladesh), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00860470 phase3completednot on this map

Antenatal Multiple Micronutrient Supplementation to Improve Infant Survival and Health in Bangladesh

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2008 to 2012Enrolled44,567ConditionsInfant Mortality, Preterm Birth, Low Birth Weight, Neonatal MortalityArmsIron (27 mg) - folic acid (600 ug), Multiple micronutrient
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  3. Associations between Nugent-bacterial vaginosis and preterm birth and other adverse pregnancy outcomes in rural northwestern Bangladesh.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  17. Primary and Repeated Respiratory Viral Infections Among Infants in Rural Nepal.Journal of the Pediatric Infectious Diseases Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alison D GernandDepartment of Nutritional Sciences, The Pennsylvania State University, 110 Chandlee Laboratory, University Park, PA, 16802, USA. adg14@psu.edu.
Rina Rani PaulThe JiVitA Maternal and Child Health and Nutrition Research Project, Godown Road, Gaibandha, Bangladesh.
Barkat UllahThe JiVitA Maternal and Child Health and Nutrition Research Project, Godown Road, Gaibandha, Bangladesh.
Muhammad A TaherCentre for Nuclear Medicine & Ultrasound, Rangpur Medical College Hospital Campus, G.P.O. Box No. 16, Rangpur, Bangladesh.
Frank R WitterDivision of Maternal-Fetal Medicine, The Johns Hopkins Hospital, 1800 Orleans St, Baltimore, MD, 21287, USA.
Lee WuDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
Alain B LabriqueDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
Keith P WestDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
Parul ChristianDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.
Johns Hopkins University · USChild Health Research Foundation · BDJohns Hopkins Hospital · USPennsylvania State University · USRangpur Medical College

Funding

Training in International Maternal and Child HealthT32HD046405 · NICHD · JOHNS HOPKINS UNIVERSITY · PI KATZ, JOANNE · 2006 to 2010
$1.3M
NICHD NIH HHS T32 HD046405
6 · The paper itself

Abstract

backgroundThe best method of gestational age assessment is by ultrasound in the first trimester; however, this method is impractical in large field trials in rural areas. Our objective was to assess the validity of gestational age estimated from prospectively collected date of last menstrual period (LMP) using crown-rump length (CRL) measured in early pregnancy by ultrasound.

methodsAs part of a large, cluster-randomized, controlled trial in rural Bangladesh, we collected dates of LMP by recall and as marked on a calendar every 5 weeks in women likely to become pregnant. Among those with a urine-test confirmed pregnancy, a subset with gestational age of <15 weeks (n = 353) were enrolled for ultrasound follow-up to measure CRL. We compared interview-assessed LMP with CRL gestational age estimates and classification of preterm, term, and post-term births.

resultsLMP-based gestational age was higher than CRL by a mean (SD) of 2.8 (10.7) days; differences varied by maternal education and preterm birth (P < 0.05). Lin's concordance correlation coefficient was good at ultrasound [0.63 (95 % CI 0.56, 0.69)] and at birth [0.77 (95 % CI 0.73, 0.81)]. Validity of classifying preterm birth was high but post-term was lower, with specificity of 96 and 89 % and sensitivity of 86 and 67 %, respectively. Results were similar by parity.

conclusionsProspectively collected LMP provided a valid estimate of gestational age and preterm birth in a rural, low-income setting and may be a suitable alternative to ultrasound in programmatic settings and large field trials.

trial registrationClinicalTrials.gov NCT00860470.

Indexed as

Gestational AgeInfant, PrematureMenstruationMental RecallRural PopulationAdolescentAdultBangladeshFemaleHumansInfant, NewbornPovertyPregnancyPregnancy TestsPrenatal CareTimeBangladeshCrown-rump lengthGestational ageLast menstrual periodUltrasoundValidation

Identifiers

PMID27769295
PMCPMC5073953
OpenAlexW2538835577

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.