Observational studyBMC pediatrics2016
Neonatal outcomes in pregnancies resulting from oocyte donation: a cohort study in Sweden.
Observational study in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Perinatal outcomes and maternal health before and after single motherhood through assisted conception: A multiregistry study in Sweden.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Pregnancy outcome and follow-up of offspring of donor oocytes recipient from PCOS patients.BMC pregnancy and childbirth · 2022Article
- Multifoetal gestations mediate the effect of in vitro fertilisation (IVF) on ischaemic placental disease in autologous oocyte IVF more than donor oocyte IVF.Paediatric and perinatal epidemiology · 2022Article
- Mothers who have given birth at an advanced age - health status before and after childbirth.Scientific reports · 2020Article
- Comparison of perinatal outcomes between spontaneous vs. commissioned cycles in gestational carriers for single and same-sex male intended parents.Journal of assisted reproduction and genetics · 2020Article
- Risk of ischemic placental disease is increased following in vitro fertilization with oocyte donation: a retrospective cohort study.Journal of assisted reproduction and genetics · 2019Article
- Epigenetically regulated imprinted gene expression associated with IVF and infertility: possible influence of prenatal stress and depression.Journal of assisted reproduction and genetics · 2019Review
- Evaluation of risk factors' importance on adverse pregnancy and neonatal outcomes in women aged 40 years or older.BMC pregnancy and childbirth · 2019Article
- How much does the uterus matter? Perinatal outcomes are improved when donor oocyte embryos are transferred to gestational carriers compared to intended parent recipients.Fertility and sterility · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnancies resulting through oocyte donation have been associated with increased risk for adverse outcomes for the mother, such as gestational hypertensive disorders. However, little is known about possible neonatal complications of such pregnancies. The purpose of this study was to evaluate the neonatal health outcomes among singleton pregnancies in a population of relatively young and healthy oocyte recipients in Sweden, taking into account the medical indication leading to treatment.
methodsThis cohort study involved 76 women conceiving with donated oocytes, 149 age-matched nulliparous women conceiving spontaneously and 63 women conceiving after non-donor IVF. Participants were recruited during 2005-2008 and followed up until delivery. Data on neonatal outcomes were retrieved from the National Birth Medical Register and the medical records of oocyte recipients from seven Swedish University Hospitals with IVF clinics. Logistic regression analyses were performed to examine the association of mode of conception and neonatal outcomes, adjusted for maternal age and BMI, gestational age and delivery by cesarean section.
resultsInfants conceived through oocyte donation had higher odds for premature delivery [OR 2.36, 95 % CI (1.02-5.45)], for being small for gestational age [OR 4.23, 95 % CI (1.03-17.42)] and having Apgar score below 7 at 5 min [OR 10.57, 95 % CI (1.21-92.20)] compared to spontaneously conceived infants. Similar trends were observed when comparing infants conceived through oocyte donation to those conceived by traditional IVF. Furthermore, donor oocyte infants had a lower mean birthweight and length compared to autologous oocyte neonates (p = 0.013); however no differences were noted among infants born at term. Neonatal outcomes were more favorable among women with diminished ovarian reserve compared to those with other indications for oocyte donation.
conclusionsInfants conceived after oocyte donation in Sweden have higher odds of being born prematurely and having lower mean birthweight in comparison to non-donor infants. It seems that these unfavorable neonatal outcomes are present despite the age, weight and health restrictions applied to recipients before oocyte donation treatment in Sweden.
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