Evidence map›Paper›PMID 27769184›Full record

ArticleBMC immunology2016

Distinct phenotypic subpopulations of circulating CD4

Deying Liu, Jinxiang Liu, Jinghua Wang, Congcong Liu, Sirui Yang, Yanfang Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  5. TFrontiers in immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Deying LiuDepartment of Pediatric Rheumatology and Allergy, The First Affiliated Bethune Hospital of Jilin University, Changchun, 130021, China.
Jinxiang LiuDepartment of Pediatric Rheumatology and Allergy, The First Affiliated Bethune Hospital of Jilin University, Changchun, 130021, China.
Jinghua WangDepartment of Pediatric Rheumatology and Allergy, The First Affiliated Bethune Hospital of Jilin University, Changchun, 130021, China.
Congcong LiuDepartment of Pediatric Rheumatology and Allergy, The First Affiliated Bethune Hospital of Jilin University, Changchun, 130021, China.
Sirui YangDepartment of Pediatric Rheumatology and Allergy, The First Affiliated Bethune Hospital of Jilin University, Changchun, 130021, China. siruiyang@163.com.
Yanfang JiangGenetic Diagnosis Center, The First Hospital of Jilin University, Changchun, 130021, China. yanfangjiang@hotmail.com.
First Bethune Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCirculating follicular helper T (Tfh) cells are a heterogeneous population of CD4

methodsAccording to the phenotypic expressions of different molecules, focus was given on six subpopulations of Tfh cells: CD4

resultsSignificantly higher frequencies of CD4

conclusionsTfh cells may differentially contribute to the development of IgAV or predict disease progression. These findings provide novel insights in the pathogenesis of IgAV and may benefit treatment development targeting organ-specific presenting symptoms of IgAV.

Indexed as

AdolescentCD4 AntigensChildChild, PreschoolDisease ProgressionFemaleGerminal CenterHumansImmunoglobulin AImmunophenotypingInterleukin-21InterleukinsMaleMolecular Targeted TherapyPhenotypeReceptors, CXCR5CD4 AntigensCXCR5 protein, humanImmunoglobulin AInterleukin-21InterleukinsReceptors, CXCR5Follicular helper T cellsGlucocorticoidIgA vasculitisInterleukin 21RemissionSymptoms

Identifiers

PMID27769184
PMCPMC5073818
OpenAlexW2539021633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.