SynthesisThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Is chronic toxoplasmosis a risk factor for diabetes mellitus? A systematic review and meta-analysis of case-control studies.
Synthesis in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Association between type-2 diabetes and Toxoplasma gondii seropositivity: a systematic review and meta-analysis.Folia parasitologica · 2025Pooled it
- Burden of intestinal parasites among diabetic patients in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Association betweenInternational journal of environmental research and public health · 2023Pooled it
- Promising effects of parasite-derived compounds on tumor regression: a systematic review of in vitro and in vivo studies.Environmental science and pollution research international · 2022Pooled it
- Toxoplasmosis seroprevalence in rheumatoid arthritis patients: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- A systematic review and meta-analysis of the prevalence of toxoplasmosis in hemodialysis patients in Iran.Epidemiology and health · 2018Pooled it
- Public Health Implications of Latent Toxoplasmosis and Its Association With Type 2 Diabetes: A Case-Control Study in Qazvin, North-Western Iran.Health science reports · 2026Article
- Beyond Latency: ChronicBiomedicines · 2025Review
- Overview of foodborne hazards associated with inflammation and metabolic health.BMC global and public health · 2025Review
- The Possible Association Between Chronic Toxoplasmosis and Type-2 Diabetes Mellitus In Women: A Case-Control Study.Cureus · 2025Article
- Toxoplasma gondii IgG serointensity and cognitive function in bipolar disorder.International journal of bipolar disorders · 2024Article
- Review
- Seroepidemiology ofJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- Effects ofFood and waterborne parasitology · 2023Article
- Association of Toxoplasmosis and COVID-19 in a MexicanPopulation.Microorganisms · 2023Article
- Intestinal parasites and diabetes: A systematic review and meta-analysis.New microbes and new infections · 2023Article
- Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus.Biomedicines · 2022Article
- The association between Toxoplasma infection and mortality: the NHANES epidemiologic follow-up study.Parasites & vectors · 2022Article
- Network pharmacology-based strategy for predicting therapy targets of Sanqi and Huangjing in diabetes mellitus.World journal of clinical cases · 2022Article
- Cross-sectional association of Toxoplasma gondii exposure with BMI and diet in US adults.PLoS neglected tropical diseases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe global protozoan parasite, Toxoplasma gondii, infects many warm-blooded animals and humans by employing different transmission routes. There have been some recent studies on the probable relevance of infectious agents and diabetes. Therefore, we conducted a systematic review and meta-analysis to identify the possible association between chronic toxoplasmosis and diabetes mellitus.
methodsThis study was conducted following the general methodology recommended for systematic reviews and meta-analysis. Nine English literature databases (Google scholar, PubMed, Scopus, Web of science, Science Direct, Ovid, ProQuest, IngentaConnect, and Wiley Online Library) were searched, up to January 2016. Random effects model was used to determine odds ratios and their 95% confidence intervals.
resultsOur review resulted in a total of seven publications meeting the inclusion criteria. Because of significant heterogeneity, we estimated a common OR by a random effects model at 1.10 (95% CI=0.13-9.57) with p=0.929 and 2.39 (95% CI=1.20-4.75) with p=0.013 for type 1 and type 2 diabetes mellitus, respectively.
conclusionDespite the limitations such as low number of studies, this meta-analysis suggests chronic toxoplasmosis as a possible risk factor for type 2 DM. However, based on random effects model no statistically significant association was observed between T. gondii and type 1 DM. It is highly recommended for researchers to carry out more accurate studies aiming to better understand this association.
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