ArticleJournal of the American Chemical Society2016
Enantioselective Palladium-Catalyzed Alkenylation of Trisubstituted Alkenols To Form Allylic Quaternary Centers.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Palladium-catalyzed enantioselective alkenylation of acyclic alkenols: Broad scope with alkenyl bromides.Science advances · 2026Article
- Article
- StereoselectiveACS organic & inorganic Au · 2025Article
- Facile construction of distal and diversified tertiary and quaternary stereocenters.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Enantioselective Hydroalkenylation and Hydroalkynylation of Alkenes Enabled by a Transient Directing Group: Catalyst Generality through Rigidification.Angewandte Chemie (International ed. in English) · 2023Article
- Mechanistic Insights on the Selectivity of the Tandem Heck-Ring-Opening of Cyclopropyldiol Derivatives.JACS Au · 2022Article
- Rate Profiling the Impact of Remote Functional Groups on the Redox-Relay Heck Reaction.Organic letters · 2021Article
- Stereoselective Remote Functionalization via Palladium-Catalyzed Redox-Relay Heck Methodologies.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Palladium catalyzed carbonylative generation of potent, pyridine-based acylating electrophiles for the functionalization of arenes to ketones.Chemical science · 2020Article
- Development and Mechanistic Interrogation of Interrupted Chain-Walking in the Enantioselective Relay Heck Reaction.Journal of the American Chemical Society · 2020Article
- Ru-catalyzed isomerization of ω-alkenylboronates towards stereoselective synthesis of vinylboronates with subsequentChemical science · 2020Article
- Enantioselective Synthesis of Alkyl Allyl Ethers via Palladium-Catalyzed Redox-Relay Heck Alkenylation ofIsrael journal of chemistry · 2020Article
- Enantioselective Synthesis of γ-Functionalized Cyclopentenones and δ-Functionalized Cycloheptenones Utilizing a Redox-Relay Heck Strategy.Advanced synthesis & catalysis · 2020Article
- Asymmetric Synthesis of 1-Tetralones Bearing A Remote Quaternary Stereocenter through Rh-Catalyzed C-C Activation of Cyclopentanones.Bulletin of the Chemical Society of Japan · 2020Article
- Synthesis of Unsaturated Silyl HeterocyclesOrganometallics · 2019Article
- Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives.Chemical science · 2019Article
- Palladium-Catalyzed Enantioselective Alkenylation of Enelactams Using a Relay Heck Strategy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
- Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters.Journal of the American Chemical Society · 2019Article
- 11-Step Total Synthesis of Teleocidins B-1-B-4.Journal of the American Chemical Society · 2019Article
- Enantioselective C2-Alkylation of Indoles through a Redox-Relay Heck Reaction of 2-Indole Triflates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
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2 authors.
Funding
Abstract
In this report, we describe the generation of remote allylic quaternary stereocenters β, γ, and δ relative to a carbonyl in high enantioselectivity. We utilize a redox-relay Heck reaction between alkenyl triflates and acyclic trisubstituted alkenols of varying chain-lengths. A wide array of terminal (E)-alkenyl triflates are suitable for this process. The utility of this functionalization is validated further by conversion of the products, via simple organic processes to access remotely functionalized chiral tertiary acid, amine, and alcohol products.
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