ArticlePloS one2016
Chronology of Onset of Mental Disorders and Physical Diseases in Mental-Physical Comorbidity - A National Representative Survey of Adolescents.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 46 citations in OpenAlex.
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- Predictors of mental illness onset in adolescents and adults with intellectual disability: A retrospective cohort study in New South Wales, Australia.The Australian and New Zealand journal of psychiatry · 2025Article
- Episodic Memories Bias Contextual Threat Inferences after Aerobic and Mind-Body Exercise.Mental health and physical activity · 2025Article
- Associations between physical diseases and subsequent mental disorders: a longitudinal study in a population-based cohort.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- The Long-Term Physical-Psychiatric Comorbidities Related to Childhood Exposure to 9/11 Trauma.International journal of environmental research and public health · 2024Article
- Sex Differences in Comorbidity Combinations in the Swedish Population.Biomolecules · 2022Article
- How to Mitigate Risk of Premature Cardiovascular Disease Among Children and Adolescents with Mental Health Conditions.Current atherosclerosis reports · 2022Review
- Article
- Mood and anxiety profiles differentially associate with physical conditions in US adolescents.Journal of affective disorders · 2022Article
- The Arizona Sexual Experiences Scale-the Thai Translation (ASEX-Thai): Reliability and validity in Thai patients with mental disorders.F1000Research · 2022Article
- Psychobiological markers of allostatic load in depressed and nondepressed mothers and their adolescent offspring.Journal of child psychology and psychiatry, and allied disciplines · 2021Article
- Canadian Chronic Disease Indicators, 2019 - Updating the data and taking into account mental health.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2019Article
- Mental Illness Among Youth With Chronic Physical Conditions.Pediatrics · 2019Article
- Mental and Addictive Disorders and Medical Comorbidities.Current psychiatry reports · 2018Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundThe objective was to estimate temporal associations between mental disorders and physical diseases in adolescents with mental-physical comorbidities.
methodsThis article bases upon weighted data (N = 6483) from the National Comorbidity Survey Adolescent Supplement (participant age: 13-18 years), a nationally representative United States cohort. Onset of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition lifetime mental disorders was assessed with the fully structured World Health Organization Composite International Diagnostic Interview, complemented by parent report. Onset of lifetime medical conditions and doctor-diagnosed diseases was assessed by self-report.
resultsThe most substantial temporal associations with onset of mental disorders preceding onset of physical diseases included those between affective disorders and arthritis (hazard ratio (HR) = 3.36, 95%-confidence interval (CI) = 1.95 to 5.77) and diseases of the digestive system (HR = 3.39, CI = 2.30 to 5.00), between anxiety disorders and skin diseases (HR = 1.53, CI = 1.21 to 1.94), and between substance use disorders and seasonal allergies (HR = 0.33, CI = 0.17 to 0.63). The most substantial temporal associations with physical diseases preceding mental disorders included those between heart diseases and anxiety disorders (HR = 1.89, CI = 1.41 to 2.52), epilepsy and eating disorders (HR = 6.27, CI = 1.58 to 24.96), and heart diseases and any mental disorder (HR = 1.39, CI = 1.11 to 1.74).
conclusionsFindings suggest that mental disorders are antecedent risk factors of certain physical diseases in early life, but also vice versa. Our results expand the relevance of mental disorders beyond mental to physical health care, and vice versa, supporting the concept of a more integrated mental-physical health care approach, and open new starting points for early disease prevention and better treatments, with relevance for various medical disciplines.
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