Evidence map›Paper›PMID 27768673›Full record

ReviewJournal of neurosurgical anesthesiology2016

Summary of the Update Session on Clinical Neurotoxicity Studies.

Teeda Pinyavat, David O Warner, Randall P Flick, Mary Ellen McCann, Dean B Andropoulos, Danquig Hu, Jeffrey W Sall, Marisa N Spann, Caleb Ing

Abstract readReview
In one paragraph

Review in Journal of neurosurgical anesthesiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Anesthetic neurotoxicity and the developing brain.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teeda PinyavatDepartments of *Anesthesiology#Psychiatry, Columbia University College of Physicians and Surgeons, New York, NYDepartments of †Anesthesiology‡Pediatrics, Mayo Clinic College of Medicine, Rochester, MN§Department of Anesthesiology, Harvard Medical School, Boston, MA∥Department of Anesthesiology and Department of Pediatrics, Baylor College of Medicine, Houston, TX¶Department of Anesthesiology and Perioperative Care, University of California San Francisco School of Medicine, San Francisco, CA.
David O Warner
Randall P Flick
Mary Ellen McCann
Dean B Andropoulos
Danquig Hu
Jeffrey W Sall
Marisa N Spann
Caleb Ing

Funding

Anesthesia Exposure and Risk of Behavioral or Developmental DisorderK08HS022941 · AHRQ · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ING, CALEB · 2014 to 2018
$632k
AHRQ HHS K08 HS022941
6 · The paper itself

Abstract

During the Fifth Pediatric Anesthesia Neurodevelopmental Assessment Symposium, experts and stakeholders met to present and discuss recent advances made in the study of neurodevelopmental outcomes after exposure to anesthetic drugs in infants and children. This article summarizes the update of 5 ongoing clinical studies: General Anesthesia compared to Spinal Anesthesia, Toxicity of Remifentanil and Dexmedetomidine, Mayo Anesthesia Safety in Kids, the University of California San Francisco human cohort study, and Columbia University Medical Center Neonatal Magnetic Resonance Imaging study. The purpose of this summary is to discuss the contributions and limitations of these studies, how they fit into the published literature, and what questions remain to be answered.

Indexed as

AnestheticsBrainChildChild, PreschoolHumansInfantInfant, NewbornNeurotoxicity SyndromesAnesthetics

Identifiers

PMID27768673
PMCPMC5077165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.