ArticleAnnals of surgery2017
Survival Benefit of Kidney Transplantation in HIV-infected Patients.
Article in Annals of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.Kidney international · 2018Guideline
- Referral for kidney transplantation: a consensus statement from the Brazilian Society of Nephrology.Jornal brasileiro de nefrologiaGuideline
- Hope for kidney transplantation in candidates with human immunodeficiency virus.World journal of transplantation · 2026Review
- Trends, center level practice, and outcomes of heart transplantation in people with HIV.JHLT open · 2026Article
- Human antibody repertoire among kidney donors with and without HIV.JCI insight · 2026Article
- Solid organ transplantation in people with HIV: Outcomes, obstacles and opportunities.HIV medicine · 2025Review
- Inflammation among kidney transplant donors with and without HIV: Multicenter HOPE in Action Consortium.Clinical immunology (Orlando, Fla.) · 2025Article
- The Association of HIV Criminalization Law and Disparities in Transplant Education among People with HIV.AIDS and behavior · 2025Article
- Breaking barriers: giving HOPE to people living with HIV and end-stage renal disease.Clinical kidney journal · 2025Article
- Safety of Kidney Transplantation from Donors with HIV.The New England journal of medicine · 2024Observational
- Infectious disease events in people with HIV receiving kidney transplantation: Analysis of the Swiss HIV Cohort Study and the Swiss Transplant Cohort Study.BMC infectious diseases · 2024Article
- Longitudinal analysis of viral dynamics in HIV+-to-HIV+ HOPE Act kidney-transplant recipients.The Journal of clinical investigation · 2024Article
- Influence of induction therapy and antiretroviral regimen on outcomes in kidney transplant recipients living with human immunodeficiency.Transplant infectious disease : an official journal of the Transplantation Society · 2024Article
- The changing landscape of HIV-associated kidney disease.Nature reviews. Nephrology · 2024Review
- Renal Transplantation in HIV-positive and HIV-negative People With Advanced Stages of Kidney Disease: Equity in Transplantation.Open forum infectious diseases · 2024Article
- Overcoming barriers and stigma: new frontiers in solid organ transplantation for people with HIV.Clinical microbiology reviews · 2024Review
- Racial Disparities in Access to the Kidney Transplant Waitlist Among People with Human Immunodeficiency Virus.AIDS patient care and STDs · 2023Article
- Management of Type 2 Diabetes Mellitus and Kidney Failure in People with HIV-Infection in Africa: Current Status and a Call to Action.HIV/AIDS (Auckland, N.Z.) · 2023Review
- Early steps to kidney transplantation among persons with HIV and end-stage renal disease in ESRD network 6.Transplant infectious disease : an official journal of the Transplantation Society · 2022Article
- Complications of rabbit anti-thymocyte globulin induction immunosuppression in HIV-infected kidney transplant recipients.Frontiers in nephrology · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveTo determine the survival benefit of kidney transplantation in human immunodeficiency virus (HIV)-infected patients with end-stage renal disease (ESRD). SUMMARY BACKGROUND DATA: Although kidney transplantation (KT) has emerged as a viable option for select HIV-infected patients, concerns have been raised that risks of KT in HIV-infected patients are higher than those in their HIV-negative counterparts. Despite these increased risks, KT may provide survival benefit for the HIV-infected patient with ESRD, yet this important clinical question remains unanswered.
methodsData from the Scientific Registry of Transplant Recipients were linked to IMS pharmacy fills (January 1, 2001 to October 1, 2012) to identify and study 1431 HIV-infected KT candidates from the first point of active status on the waiting list. Time-dependent Cox regression was used to establish a counterfactual framework for estimating survival benefit of KT.
resultsAdjusted relative risk (aRR) of mortality at 5 years was 79% lower after KT compared with dialysis (aRR 0.21; 95% CI 0.10-0.42; P <0.001), and statistically significant survival benefit was achieved by 194 days of KT. Among patients coinfected with hepatitis C, aRR of mortality at 5 years was 91% lower after KT compared with dialysis (aRR 0.09; 95% CI 0.02-0.46; P < 0.004); however, statistically significant survival benefit was not achieved until 392 days after KT.
conclusionsEvidence suggests that for HIV-infected ESRD patients, KT is associated with a significant survival benefit compared with remaining on dialysis.
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