Evidence map›Paper›PMID 27768047›Full record

ArticleJournal of visualized experiments : JoVE2016

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis.

Jürgen Keller, Martin Gorges, Helena E A Aho-Özhan, Ingo Uttner, Erich Schneider, Jan Kassubek, Elmar H Pinkhardt, Albert C Ludolph, Dorothée Lulé

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jürgen KellerDepartment of Neurology, Ulm University.
Martin GorgesDepartment of Neurology, Ulm University.
Helena E A Aho-ÖzhanDepartment of Neurology, Ulm University.
Ingo UttnerDepartment of Neurology, Ulm University.
Erich SchneiderInstitute of Medical Technology, Brandenburg University of Technology Cottbus-Senftenberg.
Jan KassubekDepartment of Neurology, Ulm University.
Elmar H PinkhardtDepartment of Neurology, Ulm University.
Albert C LudolphDepartment of Neurology, Ulm University.
Dorothée LuléDepartment of Neurology, Ulm University; dorothee.lule@uni-ulm.de.
Universität Ulm · DEBrandenburg University of Technology Cottbus-Senftenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with pathological involvement of upper and lower motoneurons, subsequently leading to progressive loss of motor and speech abilities. In addition, cognitive functions are impaired in a subset of patients. To evaluate these potential deficits in severely physically impaired ALS patients, eye-tracking is a promising means to conduct cognitive tests. The present article focuses on how eye movements, an indirect means of communication for physically disabled patients, can be utilized to allow for detailed neuropsychological assessment. The requirements, in terms of oculomotor parameters that have to be met for sufficient eye-tracking in ALS patients are presented. The properties of stimuli, including type of neuropsychological tests and style of presentation, best suited to successfully assess cognitive functioning, are also described. Furthermore, recommendations regarding procedural requirements are provided. Overall, this methodology provides a reliable, easy to administer and fast approach for assessing cognitive deficits in patients who are unable to speak or write such as patients with severe ALS. The only confounding factor might be deficits in voluntary eye movement control in a subset of ALS patients.

Indexed as

Eye MovementsNeuropsychological TestsAmyotrophic Lateral SclerosisCognitionCognition DisordersHumans

Identifiers

PMID27768047
PMCPMC5092192
OpenAlexW2530686360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.