Evidence map›Paper›PMID 27767345›Full record

ArticleCurrent eye research2017

Bayer Filter Snapshot Hyperspectral Fundus Camera for Human Retinal Imaging.

Joel Kaluzny, Hao Li, Wenzhong Liu, Peter Nesper, Justin Park, Hao F Zhang, Amani A Fawzi

Open access · greenAbstract read
In one paragraph

Article in Current eye research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Hyperspectral Imaging and the Retina: Worth the Wave?Translational vision science & technology · 2020
    Pooled it
  3. Article
  4. Retina Phantom Model for Hyperspectral Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  5. A Dual-Camera High-Resolution Hyperspectral Imaging System for the Retina.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  6. Review
  7. Review
  8. Targeted spectroscopy in the eye fundus.Journal of biomedical optics · 2023
    Article
  9. Review
  10. Advances in Retinal Oximetry.Translational vision science & technology · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joel Kaluzny *Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hao Li *Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Wenzhong LiuDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Peter NesperDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Justin ParkDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hao F ZhangDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Amani A FawziDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Northwestern University · US

Funding

Novel Antiangiogenic Peptides for Treatment of Exudative AMDR24EY022883 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI SHEIBANI, NADER · 2013 to 2017
$6.2M
Hyperspectral Imaging of the Normal and Age-related Macular Degeneration FundusR01EY021470 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FAWZI, AMANI A, SMITH, ROLAND THEODORE · 2011 to 2014
$3.4M
Multimodal Retinal Functional Imaging for Diabetic RetinopathyR01EY019951 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAWZI, AMANI A, JIAO, SHULIANG · 2011 to 2015
$3.0M
Functional Retinal Imaging to Monitor Pharmaco-Therapies in Diabetic RetinopathyDP3DK108248 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FAWZI, AMANI A, ZHANG, HAO F · 2015 to 2015
$1.9M
NEI NIH HHS R01 EY019951NEI NIH HHS R01 EY021470NEI NIH HHS R24 EY022883NIDDK NIH HHS DP3 DK108248
6 · The paper itself

Abstract

purposeTo demonstrate the versatility and performance of a compact Bayer filter snapshot hyperspectral fundus camera for in-vivo clinical applications including retinal oximetry and macular pigment optical density measurements.

methods12 healthy volunteers were recruited under an Institutional Review Board (IRB) approved protocol. Fundus images were taken with a custom hyperspectral camera with a spectral range of 460-630 nm. We determined retinal vascular oxygen saturation (sO

resultsWe successfully determined the mean sO

conclusionsWe demonstrated a single imaging tool capable of oxygen saturation and macular pigment density measurements in vivo. The unique combination of broad spectral range, high spectral-spatial resolution, rapid and robust imaging capability, and compact design make this system a valuable tool for multifunction spectral imaging that can be easily performed in a clinic setting.

Indexed as

AdultAgedAged, 80 and overDiagnostic Techniques, OphthalmologicalFemaleFluorescein AngiographyHealthy VolunteersHumansMacular PigmentMaleMiddle AgedOximetryOxygenPhotographyReproducibility of ResultsRetinaMacular PigmentOxygenHyperspectral fundus imagingmacular pigmentoximetryspectroscopy

Identifiers

PMID27767345
PMCPMC5389919
OpenAlexW2533087400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.