Evidence map›Paper›PMID 27767104›Full record

ArticleScientific reports2016

Targeting erythrocyte carbonic anhydrase and

Chiranjit Ghosh, Santanu Mandal, Gourab D Banik, Abhijit Maity, Prabuddha Mukhopadhyay, Shibendu Ghosh, Manik Pradhan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Simultaneous Sensitive Determination ofSensors (Basel, Switzerland) · 2022
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chiranjit GhoshDepartment of Chemical, Biological &Macro-Molecular Sciences, S. N. Bose National Centre for Basic Sciences, Salt Lake, JD Block, Sector III, Kolkata, 700098, India.
Santanu MandalDepartment of Chemical, Biological &Macro-Molecular Sciences, S. N. Bose National Centre for Basic Sciences, Salt Lake, JD Block, Sector III, Kolkata, 700098, India.
Gourab D BanikDepartment of Chemical, Biological &Macro-Molecular Sciences, S. N. Bose National Centre for Basic Sciences, Salt Lake, JD Block, Sector III, Kolkata, 700098, India.
Abhijit MaityDepartment of Chemical, Biological &Macro-Molecular Sciences, S. N. Bose National Centre for Basic Sciences, Salt Lake, JD Block, Sector III, Kolkata, 700098, India.
Prabuddha MukhopadhyayDepartment of Medicine, Vivekananda Institute of Medical Sciences, 99 Sarat Bose Road, Kolkata, 700027, India.
Shibendu GhoshDepartment of Medicine, Raipur Institute of Medical Sciences, Raipur, 492006, Chhattisgarh, India.
Manik PradhanDepartment of Chemical, Biological &Macro-Molecular Sciences, S. N. Bose National Centre for Basic Sciences, Salt Lake, JD Block, Sector III, Kolkata, 700098, India.
S.N. Bose National Centre for Basic Sciences · INAll India Institute of Medical Sciences Raipur · INVivekananda Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inability to envisage the acute onset and progression of type 1 diabetes (T1D) has been a major clinical stumbling block and an important area of biomedical research over the last few decades. Therefore there is a pressing need to develop a new and an effective strategy for early detection of T1D and to precisely distinguish T1D from type 2 diabetes (T2D). Here we describe the precise role of the enzymatic activity of carbonic anhydrase (CA) in erythrocytes in the pathogenesis of T1D and T2D. We show that CA activities are markedly altered during metabolism of T1D and T2D and this facilitates to the oxygen-18 (

Indexed as

AdolescentAdultBreath TestsCarbon DioxideCarbonic AnhydrasesCase-Control StudiesChildChild, PreschoolDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2ErythrocytesFemaleGlycated HemoglobinHumansIsotope LabelingKineticsCarbon DioxideCarbonic AnhydrasesGlycated Hemoglobinhemoglobin A1c protein, humanOxygen-18Oxygen Isotopes

Identifiers

PMID27767104
PMCPMC5073312
OpenAlexW2534525254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.